Asexual ploidy shifts, which describe changes in complete sets of chromosomes via a
nonsexual reproductive cycle, are widespread in nature. For example, increased ploidy …

ABSTRACT REC8 meiotic recombination protein (REC8) is a member of structural
maintenance of chromosome (SMC) protein partners, which play an important role in …

Pathogenic fungi of the genus Cryptococcus can undergo two sexual cycles, involving either
bisexual diploidization (after fusion of haploid cells of different mating type) or unisexual …

Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the
225,000 infected people each year, even with the use of antifungal therapies. Currently …

Cellular development is orchestrated by evolutionarily conserved signaling pathways, which
are often pleiotropic and involve intra-and interpathway epistatic interactions that form …

The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each
year. Survival of this basidiomycete at host CO2 concentrations has only recently been …

Fungal pathogens often undergo morphological switches, including cell size changes, to
adapt to the host environment and cause disease. The pathogenic yeast Cryptococcus …

The ubiquitin–proteasome system (UPS) mediates intracellular proteins degradation that
influences various cellular functions in eukaryotic cells. The UPS is also involved in the …

The low efficacy and side effects associated with antifungal agents have highlighted the
importance of developing immunotherapeutic approaches to treat Cryptococcus gattii …

The ubiquitin–proteasome system (UPS) mediates intracellular proteins degradation that
influences various cellular functions in eukaryotic cells. The UPS is also involved in the …