Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

The 2016 revised fourth edition of the World Health Organization (WHO) classification of
central nervous system (CNS) tumors incorporated molecular features with histologic …

Histomorphology has been a mainstay of cancer diagnosis in anatomic pathology for many
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …

Over the last decade, developments in molecular profiling have radically altered the
diagnosis, classification, and management of numerous cancer types, with primary brain …

The changes associated with malignancy are not only in cancer cells but also in
environment in which cancer cells live. Metabolic reprogramming supports tumor cell high …

The grading of gliomas based on histological features has been a subject of debate for
several decades. A consensus has not yet been reached because of technical limitations …

Brain tumors remain one of the most difficult tumors to treat and, depending on the
diagnosis, have a poor prognosis. Of brain tumors, glioblastoma (GBM) is the most common …

Context.—The diagnosis and clinical management of patients with diffuse gliomas (DGs)
have evolved rapidly over the past decade with the emergence of molecular biomarkers that …

Glioblastoma (GBM) is the most common aggressive malignant tumor in brain
neuroepithelial tumors and remains incurable. A variety of treatment options are currently …

Epigenetic changes in DNA methylation contribute to the development of many diseases,
including cancer. In glioblastoma multiforme, the most prevalent primary brain cancer and …