The mechanisms underlying kidney development in mice and humans is an area of intense
study. Insights into kidney organogenesis have the potential to guide our understanding of …

The differentiation of human pluripotent stem cells (hPSCs) towards organoids is one of the
biggest scientific advances in regenerative medicine. Kidney organoids have not only laid …

Nephron development proceeds with reciprocal interactions among three layers: nephron
progenitors (NPs), ureteric buds and stromal progenitors (SPs). We found that Foxc1 and …

Müllerian anomaly (MA) is a group of congenital anatomic abnormalities caused by
aberrations of the development process of the Müllerian duct. MA can either be isolated or …

The female reproductive tract develops from its embryonic precursor, the Müllerian duct. In
close proximity to the Müllerian duct lies the precursor for the male reproductive tract, the …

Genitourinary development is a delicately orchestrated process that begins in the embryo.
Once complete, the genitourinary system is a collection of functionally disparate organs …

Renal response to acute and chronic injury is an intricate process including a vast range of
interacting molecules and is indeed a daunting task to tackle. Unilateral ureter obstruction is …

The kidney is an essential organ that ensures bodily fluid homeostasis and removes soluble
waste products from the organism. Nephrons, the functional units of the kidney, comprise a …