Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …

Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

Despite advances in antimicrobial and anti-inflammatory therapies, inflammation and its
consequences still remain a significant problem in medicine. Acute inflammatory responses …

Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

The perception of nociceptive signals, which are translated into pain, plays a fundamental
role in the survival of organisms. Because pain is linked to a negative sensation, animals …

Lipopolysaccharides (LPS) are the main components of the external leaflet of the Gram-
negative outer membrane and consist of three different moieties: lipid A, core …

Constant exposure of the airways to inhaled pathogens requires efficient early immune
responses protecting against infections. How bacteria on the epithelial surface are detected …

Abstract Maresin-2 (MaR2) is a specialized pro-resolution lipid mediator (SPM) that reduces
neutrophil recruitment in zymosan peritonitis. Here, we investigated the analgesic effect of …

The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of
channels, is primarily localized in a subpopulation of primary sensory neurons of the …