Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans

JL Koep, CE Taylor, JS Coombes… - The Journal of …, 2022 - Wiley Online Library
Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy

X Zhu, Q Huang, A DiSpirito, T Vu, Q Rong… - Light: Science & …, 2022 - nature.com
High-speed high-resolution imaging of the whole-brain hemodynamics is critically important
to facilitating neurovascular research. High imaging speed and image quality are crucial to …

Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke

JL Fan, RC Nogueira, P Brassard… - Journal of Cerebral …, 2022 - journals.sagepub.com
Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …

Systemic physiology augmented functional near-infrared spectroscopy: a powerful approach to study the embodied human brain

F Scholkmann, I Tachtsidis, M Wolf, U Wolf - Neurophotonics, 2022 - spiedigitallibrary.org
In this Outlook paper, we explain why an accurate physiological interpretation of functional
near-infrared spectroscopy (fNIRS) neuroimaging signals is facilitated when systemic …

On the use and misuse of cerebral hemodynamics terminology using transcranial Doppler ultrasound: a call for standardization

RJ Skow, RM Brothers… - American Journal …, 2022 - journals.physiology.org
Cerebral hemodynamics, eg, cerebral blood flow, can be measured and quantified using
many different methods, with transcranial Doppler ultrasound (TCD) being one of the most …

Nitric oxide contributes to cerebrovascular shear‐mediated dilatation but not steady‐state cerebrovascular reactivity to carbon dioxide

RL Hoiland, HG Caldwell, JMJR Carr… - The Journal of …, 2022 - Wiley Online Library
Cerebrovascular CO2 reactivity (CVR) is often considered a bioassay of cerebrovascular
endothelial function. We recently introduced a test of cerebral shear‐mediated dilatation …

[HTML][HTML] Abnormal brain oxygen homeostasis in an animal model of liver disease

A Hadjihambi, C Cudalbu, K Pierzchala, D Simicic… - Jhep Reports, 2022 - Elsevier
Background & Aims Increased plasma ammonia concentration and consequent disruption of
brain energy metabolism could underpin the pathogenesis of hepatic encephalopathy (HE) …

Brain H+/CO2 sensing and control by glial cells

AV Gourine, N Dale - Glia, 2022 - Wiley Online Library
Maintenance of constant brain pH is critically important to support the activity of individual
neurons, effective communication within the neuronal circuits, and, thus, efficient processing …

Impaired dynamic cerebral autoregulation is associated with the severity of neuroimaging features of cerebral small vessel disease

Z Liu, H Ma, ZN Guo, L Wang, Y Qu… - CNS neuroscience & …, 2022 - Wiley Online Library
Aims Cerebral small vessel disease (CSVD) is characterized by functional and structural
changes in small vessels. We aimed to elucidate the relationship between dynamic cerebral …

[HTML][HTML] Cerebrovascular activity is a major factor in the cerebrospinal fluid flow dynamics

Y Wang, P van Gelderen, JA de Zwart, PS Özbay… - Neuroimage, 2022 - Elsevier
Cerebrospinal fluid (CSF) provides physical protection to the central nervous system as well
as an essential homeostatic environment for the normal functioning of neurons. Additionally …