Non-alcoholic fatty liver (NAFL) is the most common chronic liver disease. Activation of
mitogen-activated kinases (MAPK) cascade, which leads to c-Jun N-terminal kinase (JNK) …

OBJECTIVE: Ischemia (I) causes lack of oxygen delivery to the tissues, leading to hypoxia
and cellular damage. Reperfusion (R) is the re-blooded of the tissue; however, it may cause …

Renal fibrosis and inflammation are critical for the initiation and progression of hypertensive
renal disease (HRD). However, the signaling mechanisms underlying their induction are …

Liver cancer arises from the evolutionary selection of the dynamic tumor microenvironment
(TME), in which the tumor cell generally becomes more heterogeneous; however, the …

Simple Summary Chronic inflammation is known to drive cancer initiation and progression in
the liver and other organs. In different genetic mouse models, the role of the pro …

Liver fibrosis occurs during wound healing after repeated liver injury and is characterized by
extensive extracellular matrix deposition. We previously identified hyaluronan synthase 2 …

Liver fibrosis is a wound-healing response caused by the abnormal accumulation of
extracellular matrix, which is produced by activated hepatic stellate cells (HSCs). Most …

Cancer prevention using dietary phytochemicals holds great potential, particularly in the
alternative treatment of liver cancer. Our previous study found that the methanol extract of …

The hepatotoxic effect of potassium bromide (KBr) on rat liver tissues were determined, as
well as the potential protective effect of Tegillaraca granosa (T. granosa) flesh body extract …

ABSTRACT BACKGROUND: The aim of this study was to analyze the potential protective
effect of Carvedilol against liver ischemia-reperfusion (I/R) injury in rats. METHODS: A total …