Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality.
Advanced age is also associated with elevated markers of chronic inflammation and …

The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …

The systemic metabolic shifts that occur during aging and the local metabolic alterations of a
tumor, its stroma and their communication cooperate to establish a unique tumor …

Human skin is characterized by significant diversity in color and tone, which are determined
by the quantity and distribution of melanin pigment in the epidermis. Melanin absorbs and …

Background Aging is accompanied by a dramatic decline in the interleukin (IL)-2 production
capacity of human immune cells, thus making seniors more susceptible to a variety of age …

The relationship between inflammation and age-related neurocognitive changes is
significant, which may relate to the age-related immune dysfunctions characterized by the …

Systemic inflammation is an organism's response to an assault by the non-self. However,
that inflammation may predispose humans to illnesses targeted to organs, including …

There is a need to characterize the potential susceptibility of older adults to toxicity from
environmental chemical exposures. Liver xenobiotic metabolizing enzymes (XMEs) play …

Aims We aimed to study the long-term effect of neutrophils on cardiac health during the
process of natural aging. We hypothesized that neutrophil PAD4, via its role in neutrophil …

An aging immune system is associated with a significant decline in both innate and adaptive
immune function. This decline has been attributed to poor outcomes in elderly individuals …