Background. Innovative drugs targeting the PD1/PD-L1 axis have opened promising
scenarios in modern cancer therapy. Plenty of assays and scoring systems have been …

Objectives and background: Oral squamous cell carcinoma (OSCC) is a highly malignant
disease with an increasing incidence. The need to improve therapeutic strategies for …

Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas
(UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had …

Immune-checkpoint inhibitors targeting the PD-1/PD-L1 axis have brought significant clinical
benefit in many solid cancer types, including gastrointestinal malignancies. However, it has …

Pancreatic cancer is a malignancy of rising incidence, especially in developed countries due
to causes such as sedentary lifestyles, tobacco smoking and ultraprocessed high fat and …

Colorectal carcinoma (CRC) is a disease that causes significant morbidity and mortality
worldwide. To improve treatment, new biomarkers are needed to allow better patient risk …

Undifferentiated carcinoma with osteoclast‐like giant cells (UC‐OGC) is a rare malignant
neoplasm accounting for< 1% of pancreatic masses. Very few case reports and small series …

Pancreatic cancer is projected to become the second most common cause of tumor-related
death worldwide in the next decade [1]. The most common type is represented by pancreatic …

Background Undifferentiated carcinoma with osteoclast-like giant cells (UCOGCs) is a rare
subtype of pancreatic cancer (PC), and its clinicopathological characteristics are still …

Anaplastic thyroid carcinoma is an infrequent, but aggressive fatal subtype of thyroid cancer.
The osteoclastic variant of anaplastic carcinoma is a rare subtype of anaplastic carcinoma …