The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …

This review synthesizes relations between mindfulness and resting-state fMRI functional
connectivity of brain networks. Mindfulness is characterized by present-moment awareness …

Recent years have seen a profound resurgence of activity with nonhuman primates (NHPs)
to model human brain disorders. From marmosets to macaques, the study of NHP species …

Pathological anxiety is among the most difficult neuropsychiatric diseases to treat
pharmacologically, and it represents a major societal problem. Studies have implicated …

Studying higher brain function presents fundamental scientific challenges but has great
potential for impactful translation to the clinic, supporting the needs of many patients …

Childhood adversity is associated with altered or dysregulated stress reactivity; these altered
patterns of physiological functioning persist into adulthood. Evidence from both preclinical …

Background Maladaptive stress responses are important risk factors in the etiology of mood
and anxiety disorders, but exact pathomechanisms remain to be understood. Mapping …

Aims To evaluate the associations between residential greenness and glucocorticoid levels
and whether air pollutants and sex modify the relationship between greenness and …

Structural and functional abnormalities of the orbitofrontal cortex (OFC) have been
implicated in affective disorders that manifest anxiety-related symptoms. However, research …