B vitamins and their roles in gut health

KS Hossain, S Amarasena, S Mayengbam - Microorganisms, 2022 - mdpi.com
B vitamins act as coenzymes in a myriad of cellular reactions. These include energy
production, methyl donor generation, neurotransmitter synthesis, and immune functions …

Immunity boosting nutraceuticals: Current trends and challenges

S Basak, J Gokhale - Journal of Food Biochemistry, 2022 - Wiley Online Library
The immune function of the human body is highly influenced by the dietary intake of certain
nutrients and bioactive compounds present in foods. The preventive effects of these …

Women taking a folic acid supplement in countries with mandatory food fortification programs may be exceeding the upper tolerable limit of folic acid: A systematic …

C Ledowsky, A Mahimbo, V Scarf, A Steel - Nutrients, 2022 - mdpi.com
Background: In preconception and pregnancy, women are encouraged to take folic acid-
based supplements over and above food intake. The upper tolerable limit of folic acid is …

Emerging roles for folate receptor FOLR1 in signaling and cancer

FZ Nawaz, ET Kipreos - Trends in Endocrinology & Metabolism, 2022 - cell.com
Folates are B vitamins that function in one-carbon metabolism. Folate receptors are one of
three major types of folate transporters. The folate receptors FOLR1 and FOLR2 are …

[HTML][HTML] Associations between folic acid supplement use and folate status biomarkers in the first and third trimesters of pregnancy in the Maternal–Infant Research on …

MA Patti, JM Braun, TE Arbuckle… - The American Journal of …, 2022 - Elsevier
Background Achieving optimal folate status during early gestation reduces the risk of neural
tube defects (NTDs). While inadequate folate intake remains a concern, it is becoming …

Effects of maternal folate and vitamin B12 on gestational diabetes mellitus: a dose-response meta-analysis of observational studies

N Li, J Jiang, L Guo - European Journal of Clinical Nutrition, 2022 - nature.com
To comprehensively estimate the association of gestational diabetes mellitus (GDM) risk
with maternal red blood cell (RBC) folate, plasma/serum folate, dose and duration of folic …

Excessive folic acid mimics folate deficiency in human lymphocytes

KI Alnabbat, AM Fardous, DC Cabelof… - Current Issues in …, 2022 - mdpi.com
Food fortification with synthetic folic acid (FA), along with supplementation, results in a
marked increase in the population total of serum folates and unmetabolized folic acid …

Association between plasma Vitamin B5 levels and all‐cause mortality: A nested case‐control study

Y Hong, Z Zhou, N Zhang, Q He, Z Guo… - The Journal of …, 2022 - Wiley Online Library
We aimed to evaluate the prospective association of vitamin B5 with all‐cause mortality and
explore its potential modifiers in Chinese adults with hypertension. A nested, case‐control …

Association of folate intake with cardiovascular-disease mortality and all-cause mortality among people at high risk of cardiovascular-disease

X Xu, W Wei, W Jiang, Q Song, Y Chen, Y Li, Y Zhao… - Clinical Nutrition, 2022 - Elsevier
Background & aims Due to the beneficial effect of folate on cardiovascular disease (CVD),
folic acid supplementation is a more common practice among people at high-risk of CVD …

Evaluation of cardiovascular toxicity of folic acid and 6S-5-methyltetrahydrofolate-calcium in early embryonic development

Z Lian, Z Wu, R Gu, Y Wang, C Wu, Z Cheng, M He… - Cells, 2022 - mdpi.com
Folic acid (FA) is a synthetic and highly stable version of folate, while 6S-5-
methyltetrahydrofolate is the predominant form of dietary folate in circulation and is used as …