Intra-pancreatic fat deposition: bringing hidden fat to the fore
Abstract Development of advanced modalities for detection of fat within the pancreas has
transformed understanding of the role of intra-pancreatic fat deposition (IPFD) in health and …
transformed understanding of the role of intra-pancreatic fat deposition (IPFD) in health and …
Metabolic implications of pancreatic fat accumulation
Fat accumulation outside subcutaneous adipose tissue often has unfavourable effects on
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …
[HTML][HTML] Intestinal barrier function and immune homeostasis are missing links in obesity and type 2 diabetes development
S Riedel, C Pheiffer, R Johnson, J Louw… - Frontiers in …, 2022 - frontiersin.org
Noncommunicable diseases, such as type 2 diabetes (T2D), place a burden on healthcare
systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly …
systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly …
[HTML][HTML] Associations between body composition, fat distribution and metabolic consequences of excess adiposity with severe COVID-19 outcomes: observational …
Background Higher body mass index (BMI) and metabolic consequences of excess weight
are associated with increased risk of severe COVID-19, though their mediating pathway is …
are associated with increased risk of severe COVID-19, though their mediating pathway is …
Reversal and remission of T2DM–An update for practitioners
Over the past 50 years, many countries around the world have faced an unchecked
pandemic of obesity and type 2 diabetes (T2DM). As best practice treatment of T2DM has …
pandemic of obesity and type 2 diabetes (T2DM). As best practice treatment of T2DM has …
[HTML][HTML] Proteomics and phosphoproteomics of circulating extracellular vesicles provide new insights into diabetes pathobiology
The purpose of this study was to define the proteomic and phosphoproteomic landscape of
circulating extracellular vesicles (EVs) in people with normal glucose tolerance (NGT) …
circulating extracellular vesicles (EVs) in people with normal glucose tolerance (NGT) …
Fat distribution within the pancreas according to diabetes status and insulin traits
L Skudder-Hill, IR Sequeira, J Cho, J Ko, SD Poppitt… - Diabetes, 2022 - Am Diabetes Assoc
A growing body of evidence suggests that intrapancreatic fat is associated with diabetes, but
whether distribution of intrapancreatic fat across the regions of the pancreas has a …
whether distribution of intrapancreatic fat across the regions of the pancreas has a …
[HTML][HTML] Galectin-1 in obesity and type 2 diabetes
E Fryk, VRR Silva, PA Jansson - Metabolites, 2022 - mdpi.com
Galectin-1 is a carbohydrate-binding protein expressed in many tissues. In recent years,
increasing evidence has emerged for the role of galectin-1 in obesity, insulin resistance and …
increasing evidence has emerged for the role of galectin-1 in obesity, insulin resistance and …
[HTML][HTML] Not control but conquest: strategies for the remission of type 2 diabetes mellitus
J Kim, HS Kwon - Diabetes & metabolism journal, 2022 - synapse.koreamed.org
A durable normoglycemic state was observed in several studies that treated type 2 diabetes
mellitus (T2DM) patients through metabolic surgery, intensive therapeutic intervention, or …
mellitus (T2DM) patients through metabolic surgery, intensive therapeutic intervention, or …
[HTML][HTML] Remission as an emerging therapeutic target in type 2 diabetes in the era of New glucose-lowering agents: Benefits, challenges, and treatment approaches
D Vasdeki, T Koufakis, G Tsamos, L Busetto… - Nutrients, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a progressive disease with a growing prevalence,
associated with an increased risk of complications. The introduction of new classes of …
associated with an increased risk of complications. The introduction of new classes of …