[HTML][HTML] Updating insights into the regulatory mechanisms of calcineurin-activated transcription factor Crz1 in pathogenic fungi

Y Yang, P Xie, Y Li, Y Bi, DB Prusky - Journal of Fungi, 2022 - mdpi.com
Ca2+, as a second messenger in cells, enables organisms to adapt to different
environmental stresses by rapidly sensing and responding to external stimuli. In recent …

CRZ1 transcription factor is involved in cell survival, stress tolerance, and virulence in fungi

S Gupta, A Kumar, R Tamuli - Journal of Biosciences, 2022 - Springer
The calcineurin-CRZ1 signaling pathway is conserved from yeasts to humans, and is
involved in survival, tolerance to biotic and abiotic stress conditions, virulence, and drug …

The calcineurin-responsive transcription factor Crz1 is required for regulation of infection structure differentiation, calcium homeostasis and cell wall integrity in …

Y Yang, P Xie, J Yuan, Y Liu, M Zhang, Y Li, Y Bi… - Postharvest Biology and …, 2022 - Elsevier
Ca 2+/calcineurin signaling pathway is crucial in regulating growth, stress response and
pathogenicity of phytopathogenic fungi. However, there is little information about the …

[HTML][HTML] CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant …

A Ceballos-Garzon, E Roman, J Pla, F Pagniez… - Plos one, 2022 - journals.plos.org
Invasive fungal infections, which kill more than 1.6 million patients each year worldwide, are
difficult to treat due to the limited number of antifungal drugs (azoles, echinocandins, and …