The autonomic nervous system regulates cardiac function by balancing the actions of
sympathetic and parasympathetic inputs to the heart. Intrinsic cardiac neurocircuits integrate …

The ANTHEM-HF, INOVATE-HF, and NECTAR-HF clinical studies of autonomic regulation
therapy (ART) using vagus nerve stimulation (VNS) systems have collectively provided dose …

Abstract Background and Objective The cardiac autonomic nervous system (CANS) plays an
important role in the pathophysiology of atrial fibrillation (AF). Cardiovascular disease can …

The cardiovascular system and the central nervous system (CNS) closely cooperate in the
regulation of primary vital functions. The autonomic nervous system and several compounds …

Coronary heart disease and psychological stress factors such as depression are prevalent
and associated with high morbidity/mortality; they are also challenging to manage …

Maladaptation of the sympathetic nervous system contributes to the progression of
cardiovascular disease and risk for sudden cardiac death, the leading cause of mortality …

Background Mapping the structure/function organization of the cardiac nervous system is
foundational for implementation of targeted neuromodulation-based therapeutics for the …

Neural control of the heart involves continuous modulation of cardiac mechanical and
electrical activity to meet the organism's demand for blood flow. The closed-loop control …

The interconnections between brain and heart are increasingly recognized. Takotsubo
cardiomyopathy, also known as “broken heart syndrome”, is characterized by a …

Cardiovascular and psychiatric disorders are among the most commonly treated conditions
worldwide. Research in neurocardiology, psychiatry, and epidemiology have defined …