Controlled human infection models to accelerate vaccine development
RKM Choy, AL Bourgeois… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …
[HTML][HTML] Mucosal immunity to poliovirus
RI Connor, EB Brickley, WF Wieland-Alter… - Mucosal …, 2022 - Elsevier
A cornerstone of the global initiative to eradicate polio is the widespread use of live and
inactivated poliovirus vaccines in extensive public health campaigns designed to prevent …
inactivated poliovirus vaccines in extensive public health campaigns designed to prevent …
[HTML][HTML] Assessment of serological responses following vaccination campaigns with type 2 novel oral polio vaccine: a population-based study in Tajikistan in 2021
A Mirzoev, GR Macklin, Y Zhang, BA Mainou… - The Lancet Global …, 2022 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) was used to control an outbreak
of type 2 circulating vaccine derived poliovirus (cVDPV2) in Tajikistan, in 2021. We …
of type 2 circulating vaccine derived poliovirus (cVDPV2) in Tajikistan, in 2021. We …
Randomized Controlled Clinical Trial of Bivalent Oral Poliovirus Vaccine and Inactivated Poliovirus Vaccine in Nigerian Children
BN Tagbo, H Verma, ZM Mahmud… - The Journal of …, 2022 - academic.oup.com
Background We conducted a trial in Nigeria to assess the immunogenicity of the new
bivalent oral poliovirus vaccine+ inactivated poliovirus vaccine (bOPV+ IPV) immunization …
bivalent oral poliovirus vaccine+ inactivated poliovirus vaccine (bOPV+ IPV) immunization …
[HTML][HTML] Poliovirus Immunity among Children Aged 6–11 and 36–48 Months in 14 Polio High-Risk Provinces of Afghanistan: A Health-Facility-Based Study
SB Soofi, M Martinez, NH Farag, WS Hendley… - Vaccines, 2022 - mdpi.com
Afghanistan is one of two countries where wild poliovirus (WPV) type 1 remains endemic.
We conducted a facility-based cross-sectional survey of antipoliovirus antibodies in children …
We conducted a facility-based cross-sectional survey of antipoliovirus antibodies in children …
[PDF][PDF] A Network Meta-analysis of Vaccine Schedules and the Effect on Humoral and Intestinal Immunity Against Poliovirus
GR Macklin, NC Grassly, RW Sutter… - … against type-2 …, 2022 - researchonline.lshtm.ac.uk
The eradication of wild and vaccine-derived poliovirus requires the global withdrawal of oral
poliovirus vaccine (OPV) and replacement with inactivated poliovirus vaccine (IPV). The first …
poliovirus vaccine (OPV) and replacement with inactivated poliovirus vaccine (IPV). The first …
[PDF][PDF] sequelae and the eradication program
MM Peel - academia.edu
Epidemics of paralytic poliomyelitis (polio) first emerged in the late 19th and early 20th
centuries in the United States and the Scandinavian countries. They continued through the …
centuries in the United States and the Scandinavian countries. They continued through the …