Maternal metabolic adaptations during pregnancy ensure appropriate nutrient supply to the
developing fetus. This is facilitated by reductions in maternal peripheral insulin sensitivity …

Diabetes is associated with an increased risk of heart failure (HF). This is commonly termed
diabetic cardiomyopathy and is often characterised by increased cardiac fibrosis …

Objective Adiponectin, which is secreted from adipose tissue, is a protein hormone.
Although a large body of studies have found that circulating adiponectin levels increase in …

Infants born to obese mothers have a greater risk for childhood obesity and insulin
resistance. However, the underlying biological mechanism remains elusive, which …

Aims Limited data are available about the functions and expressions of leptin and
adiponectin receptors (LEPR, AdipoRs) in the uterus. Our aim was to investigate the effects …

Purpose Adiponectin may be an important indicator in the regulation of fetal and neonatal
growth due to its metabolism, energy balance, and insulin-sensitizing action. The current …

Objectives. Gestational diabetes mellitus (GDM) is glucose intolerance detected initially
during pregnancy. GDM poses an increased risk for the development of diabetes later in life …

For decades, adipose tissue was only known as an energy reservoir. Following the
discovery of leptin in 1994, a new concept was adopted based on the secretory functions of …

Introdução: Considerada uma doença crônica e multifatorial, a obesidade é um dos
principais problemas de saúde pública no mundo. Além do excesso de gordura corporal, a …