Macrophages in atherosclerotic lesions promote plaque progression and are an attractive
therapeutic target in cardiovascular research. Here we present a protocol for synthesis of …

ABSTRACT RNA-based therapeutics are emerging as a powerful platform for the treatment
of multiple diseases. Currently, the two main categories of nucleic acid therapeutics …

Small interfering RNA (siRNA) therapy has been considered as a promising strategy for
treatment of glioblastoma (GBM), which is an aggressive brain disease with poor prognosis …

Purpose In recent years, a variety of nanoparticles with excellent anticancer and delivery
properties have emerged for cancer therapy. However, potential toxicity, high production …

Based on predictable, complementary base pairing, DNA can be artificially pre-designed
into versatile DNA nanostructures of well-defined shapes and sizes. With excellent …

The development of DNA nanotechnology has attracted tremendous attention in
biotechnological and biomedical fields involving biosensing, bioimaging and disease …

The development of effective drug delivery system is highly important for targeted tumor
therapy. Over the past few decades, a number of biomaterials have been extensively …

DNA is a biological polymer that encodes and stores genetic information in all living
organism. Particularly, the precise nucleobase pairing inside DNA is exploited for the self …

Attaching DNA/RNA to nanomaterials is the basis for nucleic acid-based assembly and drug
delivery. Herein, we report that small interfering RNA (siRNA) effectively coordinates with …

Epithelial cell adhesion molecules (EpCAMs) play pivotal roles in tumorigenesis in many
cancer types, which is reported to reside within nano-to microscale membrane domains …