[HTML][HTML] HSP90 modulates T2R bitter taste receptor nitric oxide production and innate immune responses in human airway epithelial cells and macrophages
Bitter taste receptors (T2Rs) are G protein-coupled receptors (GPCRs) expressed in various
cell types including ciliated airway epithelial cells and macrophages. T2Rs in these two …
cell types including ciliated airway epithelial cells and macrophages. T2Rs in these two …
Taste receptors in chronic rhinosinusitus, what is the evidence? A systematic review
JH Chen, CI Song, N Hura… - International forum of …, 2022 - Wiley Online Library
Background Bitter and sweet taste receptors (T2Rs and T1Rs), respectively, are involved in
the innate immune response of the sinonasal cavity and associated with chronic …
the innate immune response of the sinonasal cavity and associated with chronic …
Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells
J Lee, SJ Kim, GE Choi, E Yi, HJ Park… - Clinical and …, 2022 - Wiley Online Library
Background Eosinophilic inflammation is a hallmark of refractory chronic rhinosinusitis
(CRS) and considered a major therapeutic target. Autophagy deficiency in myeloid cells …
(CRS) and considered a major therapeutic target. Autophagy deficiency in myeloid cells …
[HTML][HTML] TAS2R38 Bitter Taste Receptor Expression in Chronic Rhinosinusitis with Nasal Polyps: New Data on Polypoid Tissue
J Jeruzal-Świątecka, E Borkowska… - International Journal of …, 2022 - mdpi.com
Studies have shown differences in TAS2R38 receptor expression in patients with chronic
rhinosinusitis (CRS) compared to healthy controls. Known agonists of TAS2R38 stimulate …
rhinosinusitis (CRS) compared to healthy controls. Known agonists of TAS2R38 stimulate …
Year in review: 2021 IFAR article summary.
NR Rowan, DM Beswick - International Forum of Allergy & …, 2022 - search.ebscohost.com
Nnabue et al. 16 used histological techniques and high-resolution confocal microscopy to
demonstrate a significant decrease in gland density in the posterior septum of patients with …
demonstrate a significant decrease in gland density in the posterior septum of patients with …
Akt activator SC79 stimulates antibacterial nitric oxide production from human nasal epithelial cells and increases macrophage phagocytosis in vitro
Background The role of the Akt serine/threonine kinase family in airway innate immunity is
relatively unstudied compared with other pathways. Akt can phosphorylate and activate the …
relatively unstudied compared with other pathways. Akt can phosphorylate and activate the …