Circulating tumor DNA in lymphoma: principles and future directions

M Roschewski, D Rossi, DM Kurtz, AA Alizadeh… - Blood Cancer …, 2022 - AACR
Lymphomas are heterogeneous tumors with striking genetic diversity and variable outcomes
even within pathologic diagnoses. Treatment response assessment relies on radiologic and …

Circulating tumour cells, cell free DNA and tumour-educated platelets as reliable prognostic and management biomarkers for the liquid biopsy in multiple myeloma

A Allegra, G Cancemi, G Mirabile, A Tonacci… - Cancers, 2022 - mdpi.com
Simple Summary Even though the presently employed biomarkers in the detection and
management of multiple myeloma are demonstrating encouraging results, the mortality …

The minimal residual disease using liquid biopsies in hematological malignancies

R Colmenares, N Álvarez, S Barrio, J Martínez-López… - Cancers, 2022 - mdpi.com
Simple Summary Monitoring the response to treatment in hematologic malignancies is
essential in defining the best way to optimize patient management. In general, achieving a …

Circulating tumor DNA profiling of a diffuse large B cell lymphoma patient with secondary acute myeloid leukemia

IA Kerle, L Jägerhuber, R Secci, N Pfarr, P Blüm… - Cancers, 2022 - mdpi.com
Simple Summary Liquid biopsy is a diagnostic procedure in which a blood sample taken
from a cancer patient is searched for cell-free DNA that originates from tumor cells in the …

[HTML][HTML] Controversies in the interpretation of liquid biopsy data in lymphoma

MC Pirosa, S Borchmann, F Jardin, G Gaidano… - …, 2022 - journals.lww.com
The rapid evolution of genomic technologies over the last years has led to the development
of different methods for the detection, measurement and analysis of cell-free DNA fragments …

A retrospective analysis of EBV‐DNA status with the prognosis of lymphoma

L Qiu, J Si, J Kang, Z Chen… - Journal of Cellular …, 2022 - Wiley Online Library
Epstein–Barr virus (EBV) infection is proved to be associated with clinicopathology of
lymphoma. However, little is known about the relationship between EBV‐DNA status after …

Serum cell-free DNA concentration as a possible prognostic marker in newly diagnosed diffuse large B-cell lymphoma

Y Shirouchi, Y Mishima, T Takayama, S Minowa… - Biomedical …, 2022 - jstage.jst.go.jp
Cell-free DNA (cfDNA) is a fragment of DNA circulating in the blood, and its concentration is
often elevated in cancer patients. To investigate the relationships between serum cfDNA …

Liquid biopsy in cancer: focus on lymphoproliferative disorders

FD Savino, F Rigali, V Giustini, D D'Aliberti, S Spinelli… - Cancers, 2022 - mdpi.com
Simple Summary Liquid biopsy (LBx) is a novel and promising approach in precision
medicine, suitable for patient management in a wide range of medical conditions. Its utility in …

ctDNA Is Useful to Detect Mutations at Codon 641 of Exon 16 of EZH2, a Biomarker for Relapse in Patients with Diffuse Large B-Cell Lymphoma

J Díaz-Chávez, O Gutiérrez-Hernández, L Taja-Chayeb… - Cancers, 2022 - mdpi.com
Simple Summary It is well known that epigenetic modifications and proteins involved in this
process are important in the biogenesis of diffuse large B-cell lymphoma. In this sense, we …

Liquid biopsy in diffuse large B-cell lymphoma: utility in cell origin determination and survival prediction in Chinese patients

M Li, N Ding, L Mi, Y Shi, X Du, Y Yi, L Yang… - Leukemia & …, 2022 - Taylor & Francis
The utility of circulating tumor DNA (ctDNA) in classifying the cell origin of diffuse large B-cell
lymphoma (DLBCL) has not been explored in the Chinese population. In this study, we …