The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity
Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
a variety of cell types, whose activity and interplay must be precisely mediated for effective …
[HTML][HTML] The role of the BTLA-HVEM complex in the pathogenesis of autoimmune diseases
K Wojciechowicz, M Spodzieja, KA Lisowska… - Cellular …, 2022 - Elsevier
Autoimmune diseases constitute a heterogeneous group of disorders with one common
feature–the loss of immune tolerance towards autoantigens. Due to the complexity of the …
feature–the loss of immune tolerance towards autoantigens. Due to the complexity of the …
Lymphocyte activation gene-3 (LAG-3) regulatory T cells: An evolving biomarker for treatment response in autoimmune diseases
S Gertel, A Polachek, O Elkayam, V Furer - Autoimmunity Reviews, 2022 - Elsevier
Regulatory T cells (Tregs) comprise a CD4+ CD25+ Foxp3+ T cell subset for maintaining
immune tolerance, and their deficits and/or dysfunction are observed in autoimmune …
immune tolerance, and their deficits and/or dysfunction are observed in autoimmune …
'Transfersome-embedded-gel'for dual-mechanistic delivery of anti-psoriatic drugs to dermal lymphocytes
Aim Develop a platform for co-delivering clobetasol propionate (CP) and cyclosporine (CyA)
to the epidermis and dermis to treat psoriasis. Methods The transfersomes were prepared by …
to the epidermis and dermis to treat psoriasis. Methods The transfersomes were prepared by …
Nobel Prize for immune checkpoint inhibitors, understanding the immunological switching between immunosuppression and autoimmunity
IG Motofei - Expert opinion on drug safety, 2022 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) are a revolutionary form of
immunotherapy in cancer. However, the percentage of patients responding to therapy is …
immunotherapy in cancer. However, the percentage of patients responding to therapy is …
ATG16L1 is a potential prognostic biomarker and immune signature for osteosarcoma: a study based on bulk rna and single-cell RNA-sequencing
Z Qin, K Luo, Y Liu, S Liao, J He, M He… - … Journal of General …, 2022 - Taylor & Francis
Background Osteosarcoma is a common solid malignancy of the bone in children and
adolescents, and its metastasis and recurrence are the principal causes of poor treatment …
adolescents, and its metastasis and recurrence are the principal causes of poor treatment …