SARS-CoV-2-mediated neuropathogenesis, deterioration of hippocampal neurogenesis and dementia

RK Radhakrishnan… - American Journal of …, 2022 - journals.sagepub.com
A significant portion of COVID-19 patients and survivors display marked clinical signs of
neurocognitive impairments. SARS-CoV-2-mediated peripheral cytokine storm and its …

A Baldwin interpretation of adult hippocampal neurogenesis: from functional relevance to physiopathology

DN Abrous, M Koehl, M Lemoine - Molecular psychiatry, 2022 - nature.com
Hippocampal adult neurogenesis has been associated to many cognitive, emotional, and
behavioral functions and dysfunctions, and its status as a selected effect or an “appendix of …

The Long Non-Coding RNA GOMAFU in Schizophrenia: Function, Disease Risk, and Beyond

PM Zakutansky, Y Feng - Cells, 2022 - mdpi.com
Neuropsychiatric diseases are among the most common brain developmental disorders,
represented by schizophrenia (SZ). The complex multifactorial etiology of SZ remains poorly …

Effects of involuntary and voluntary exercise in combination with Acousto-optic stimulation on adult neurogenesis in an Alzheimer's mouse model

W Li, J Gao, SY Lin, S Pan, B Xiao, Y Ma, K Xie… - Molecular …, 2022 - Springer
Single-factor intervention, such as physical exercise and auditory and visual stimulation,
plays a positive role on the prevention and treatment of Alzheimer's disease (AD); however …

Adult neural stem cell regulation by small non-coding RNAs: physiological significance and pathological implications

A Penning, G Tosoni, O Abiega, P Bielefeld… - Frontiers in Cellular …, 2022 - frontiersin.org
The adult neurogenic niches are complex multicellular systems, receiving regulatory input
from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways …

Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood–brain …

H Hu, X Yang, Y He, C Duan, N Sun - Journal of Neuroinflammation, 2022 - Springer
Background Psychological stress is one of the most important factors that trigger emotional
disorders, such as depression and anxiety. Emerging evidence suggests that …

ULK4 in neurodevelopmental and neuropsychiatric disorders

S Luo, N Zheng, B Lang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The gene Unc51-like kinase 4 (ULK4) belongs to the Unc-51-like serine/threonine kinase
family and is assumed to encode a pseudokinase with unclear function. Recently, emerging …

[HTML][HTML] Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy

MN Arshad, S Oppenheimer, J Jeong… - Neurobiology of …, 2022 - Elsevier
GABAergic interneurons play a role in regulating adult neurogenesis within the dentate
gyrus (DG) of the hippocampus. Neurogenesis occurs within a stem cell niche in the …

Steroid hormones and hippocampal neurogenesis in the adult mammalian brain

TE Hodges, TA Puri, SA Blankers, W Qiu… - Vitamins and …, 2022 - Elsevier
Hippocampal neurogenesis persists across the lifespan in many species, including rodents
and humans, and is associated with cognitive performance and the pathogenesis of …

Exposure to deltamethrin at the NOAEL causes ER stress and disruption of hippocampal neurogenesis in adult mice

MM Hossain, A Belkadi, X Zhou, E DiCicco-Bloom - NeuroToxicology, 2022 - Elsevier
In addition to age and traumatic brain injury, environmental exposure to pesticides is a
potential risk factor for neurodegenerative diseases and cognitive impairments in humans …