Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver …
Polyunsaturated fatty acids (PUFA) play essential roles in cell membrane structure and
physiological processes including signal transduction, cellular metabolism and tissue …
physiological processes including signal transduction, cellular metabolism and tissue …
[HTML][HTML] Stearoyl-CoA Desaturase-1 dependent lipid droplets accumulation in cancer-associated fibroblasts facilitates the progression of lung cancer
Y Zhang, Z Gu, J Wan, X Lou, S Liu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Abstract Rationale: Cancer-associated fibroblasts (CAFs) are the main components in the
tumor microenvironment (TME) and facilitate lung cancer progression. Studies have …
tumor microenvironment (TME) and facilitate lung cancer progression. Studies have …
Glioblastoma Multiforme Tumors in Women Have a Lower Expression of Fatty Acid Elongases ELOVL2, ELOVL5, ELOVL6, and ELOVL7 than in Men
J Korbecki, D Simińska, D Jeżewski, K Kojder… - Brain Sciences, 2022 - mdpi.com
One line of research on the possible ways of inhibiting the growth of glioblastoma multiforme
(GBM), a brain tumor with a very poor prognosis, is the analysis of its metabolism, such as …
(GBM), a brain tumor with a very poor prognosis, is the analysis of its metabolism, such as …
Integrative analysis of lncRNA-miRNA-mRNA regulatory network reveals the key lncRNAs implicated potentially in the differentiation of adipocyte in goats
C He, Y Wang, J Zhu, Y Li, J Chen, Y Lin - Frontiers in Physiology, 2022 - frontiersin.org
Goats are popular in China because of their superior meat quality, delicate flesh, and unique
flavor. Long noncoding RNAs (lncRNAs) play important roles in transcriptional and post …
flavor. Long noncoding RNAs (lncRNAs) play important roles in transcriptional and post …
Characterization of the chicken melanocortin 5 receptor and its potential role in regulating hepatic glucolipid metabolism
X Zhang, J Su, T Huang, X Wang, C Wu, J Li… - Frontiers in …, 2022 - frontiersin.org
Melanocortin receptors (MC1R-MC5R) and their accessory proteins (MRAPs) are involved
in a variety of physiological processes, including pigmentation, lipolysis, adrenal …
in a variety of physiological processes, including pigmentation, lipolysis, adrenal …
Ganoderma lucidum protease hydrolyzate on lipid metabolism and gut microbiota in high-fat diet fed rats
Y Xiong, FL Zhang, JR Li, PZ Peng, B Liu, LN Zhao - Food Bioscience, 2022 - Elsevier
In this study, we aimed to evaluate the effect of Ganoderma lucidum protease hydrolysate
(GLPH) on lipid metabolism and intestinal flora in rats fed on a high-fat diet. Our research …
(GLPH) on lipid metabolism and intestinal flora in rats fed on a high-fat diet. Our research …
Metabolic Profiling Analysis of Liver in Landes Geese During the Formation of Fatty Liver via GC-TOF/MS
Y Yu, W Lyu, Z Fu, Q Fan, Y Xiao, Y Ren… - Frontiers in …, 2022 - frontiersin.org
Fatty liver production results from the process of overfeeding geese, inducing a dramatic
increase in de novo liver lipogenesis. To investigate the alteration of liver metabolites by …
increase in de novo liver lipogenesis. To investigate the alteration of liver metabolites by …
Insulin can up-regulate LC-PUFA biosynthesis with the involvement of Srebp-1c and stimulatory protein 1 (Sp1) in marine teleost Siganus canaliculatus
Y Dong, L Liu, M Li, D Xie, J Zhao, S Wang, C You, Y Li - Gene, 2022 - Elsevier
The rabbitfish Siganus canaliculatus is the first marine teleost found to have the biosynthetic
ability of long-chain polyunsaturated fatty acids (LC-PUFA) from C 18 precursors catalyzed …
ability of long-chain polyunsaturated fatty acids (LC-PUFA) from C 18 precursors catalyzed …
Determinants of the Omega-3 Index in the UK Biobank
JP Schuchardt, N Tintle, J Westra, WS Harris - medRxiv, 2022 - medrxiv.org
Abstract Information on the Omega-3 Index (O3I) in the United Kingdom (UK) are scarce.
The UK-Biobank (UKBB) contains data on total plasma omega-3 polyunsaturated fatty acids …
The UK-Biobank (UKBB) contains data on total plasma omega-3 polyunsaturated fatty acids …
[HTML][HTML] 利用PiggyBac 转座子系统构建表达Δ15 Des 酶活性的转基因小鼠
王颖， 杨仕赛， 赵瑄， 李亚， 吕露露， 朱贵明 - 生物工程学报, 2022 - cjb.ijournals.cn
必需脂肪酸为人体健康和生命所必需, 但机体自身不能合成, 研究表明ω-3
族脂肪酸对人体的生理功能有更加积极的影响. 哺乳动物体内缺乏ω-3 去饱和酶的基因 …
族脂肪酸对人体的生理功能有更加积极的影响. 哺乳动物体内缺乏ω-3 去饱和酶的基因 …