[HTML][HTML] The role of biofilm formation in the pathogenesis and antimicrobial susceptibility of Cutibacterium acnes

T Coenye, KJ Spittaels, Y Achermann - Biofilm, 2022 - Elsevier
Cutibacterium acnes (previously known as Propionibacterium acnes) is frequently found on
lipid-rich parts of the human skin. While C. acnes is most known for its role in the …

[HTML][HTML] Strategies to mitigate and treat orthopaedic device-associated infections

DG Kennedy, AM O'Mahony, EP Culligan… - Antibiotics, 2022 - mdpi.com
Orthopaedic device implants play a crucial role in restoring functionality to patients suffering
from debilitating musculoskeletal diseases or to those who have experienced traumatic …

[HTML][HTML] Microbiology of hip and knee periprosthetic joint infections: a database study

DBG Tai, R Patel, MP Abdel, EF Berbari… - Clinical Microbiology and …, 2022 - Elsevier
Objectives Knowledge of the microbiological aetiology of periprosthetic joint infection (PJI) is
essential to its management. Contemporary literature from the United States on this topic is …

Diagnosis and treatment of culture-negative periprosthetic joint infection

GS Goh, J Parvizi - The Journal of Arthroplasty, 2022 - Elsevier
Identification of the causative organism (s) in periprosthetic joint infection (PJI) is a
challenging task. The shortcomings of traditional cultures have been emphasized in recent …

Comparison of the BioFire joint infection panel to 16S ribosomal RNA gene-based targeted metagenomic sequencing for testing synovial fluid from patients with knee …

MA Azad, MJ Wolf, AP Strasburg… - Journal of clinical …, 2022 - Am Soc Microbiol
The diagnosis of periprosthetic joint infection (PJI) is challenging, often requiring multiple
clinical specimens and diagnostic techniques, some with prolonged result turnaround times …

Clinical metagenomic sequencing for species identification and antimicrobial resistance prediction in orthopedic device infection

TL Street, ND Sanderson, C Kolenda… - Journal of clinical …, 2022 - Am Soc Microbiol
Diagnosis of orthopedic device-related infection is challenging, and causative pathogens
may be difficult to culture. Metagenomic sequencing can diagnose infections without culture …

Enhancing diagnostics in orthopedic infections

E Higgins, GA Suh, AJ Tande - Journal of Clinical Microbiology, 2022 - Am Soc Microbiol
Accurate diagnosis of orthopedic infection is crucial in guiding both antimicrobial therapy
and surgical management in order to optimize patient outcomes. A variety of microbiological …

Current and novel diagnostics for orthopedic implant biofilm infections: a review

D Ronin, J Boyer, N Alban, RM Natoli, A Johnson… - APMIS, 2022 - Wiley Online Library
Biofilm infections involving orthopedic implants are a global problem. They contribute to
severe complications and mortality, as well as increased use of antibiotic treatments and …

[HTML][HTML] Orthopaedic implant-associated staphylococcal infections: a critical reappraisal of unmet clinical needs associated with the implementation of the best …

M Gatti, S Barnini, F Guarracino, EM Parisio, M Spinicci… - Antibiotics, 2022 - mdpi.com
Infections associated with orthopaedic implants represent a major health concern
characterized by a remarkable incidence of morbidity and mortality. The wide variety of …

[HTML][HTML] A review of current practices in periprosthetic joint infection debridement and revision arthroplasty

HM Mian, JG Lyons, J Perrin, AW Froehle… - Arthroplasty, 2022 - Springer
Background Periprosthetic joint infection remains a significant challenge for arthroplasty
surgeons globally. Over the last few decades, there has been much advancement in terms of …