[HTML][HTML] Protective mechanisms and current clinical evidence of hypothermic oxygenated machine perfusion (HOPE) in preventing post-transplant cholangiopathy
A Schlegel, RJ Porte, P Dutkowski - Journal of Hepatology, 2022 - Elsevier
The development of cholangiopathies after liver transplantation impacts on the quality and
duration of graft and patient survival, contributing to higher costs as numerous interventions …
duration of graft and patient survival, contributing to higher costs as numerous interventions …
Machine perfusion of the liver: applications in transplantation and beyond
CDL Ceresa, D Nasralla, JM Pollok… - Nature reviews …, 2022 - nature.com
The shortage of donor livers considered suitable for transplantation has driven the
development of novel methods for organ preservation and reconditioning. Machine …
development of novel methods for organ preservation and reconditioning. Machine …
Impact of portable normothermic blood-based machine perfusion on outcomes of liver transplant: the OCS liver PROTECT randomized clinical trial
JF Markmann, MS Abouljoud, RM Ghobrial… - JAMA …, 2022 - jamanetwork.com
Importance Ischemic cold storage (ICS) of livers for transplant is associated with serious
posttransplant complications and underuse of liver allografts. Objective To determine …
posttransplant complications and underuse of liver allografts. Objective To determine …
Transplantation of a human liver following 3 days of ex situ normothermic preservation
Current organ preservation methods provide a narrow window (usually< 12 hours) to
assess, transport and implant donor grafts for human transplantation. Here we report the …
assess, transport and implant donor grafts for human transplantation. Here we report the …
[HTML][HTML] Abdominal normothermic regional perfusion in controlled donation after circulatory determination of death liver transplantation: outcomes and risk factors for …
AJ Hessheimer, G de la Rosa, M Gastaca… - American Journal of …, 2022 - Elsevier
Postmortem normothermic regional perfusion (NRP) is a rising preservation strategy in
controlled donation after circulatory determination of death (cDCD). Herein, we present …
controlled donation after circulatory determination of death (cDCD). Herein, we present …
Liver transplantation outcomes from controlled circulatory death donors: SCS vs in situ NRP vs ex situ NMP
R Gaurav, AJ Butler, V Kosmoliaptsis… - Annals of …, 2022 - journals.lww.com
Objective: To compare the outcomes of livers donated after circulatory death (DCD) and
undergoing either in situ normothermic regional perfusion (NRP) or ex situ normothermic …
undergoing either in situ normothermic regional perfusion (NRP) or ex situ normothermic …
Sequential hypothermic and normothermic machine perfusion enables safe transplantation of high‐risk donor livers
OB van Leeuwen, SB Bodewes… - American Journal of …, 2022 - Wiley Online Library
Ex situ normothermic machine perfusion (NMP) is increasingly used for viability assessment
of high‐risk donor livers, whereas dual hypothermic oxygenated machine perfusion …
of high‐risk donor livers, whereas dual hypothermic oxygenated machine perfusion …
[HTML][HTML] Outcome of liver transplantation with grafts from brain-dead donors treated with dual hypothermic oxygenated machine perfusion, with particular reference to …
D Patrono, D Cussa, V Sciannameo… - American Journal of …, 2022 - Elsevier
Prompted by the utilization of extended criteria donors, dual hypothermic oxygenated
machine perfusion (D-HOPE) was introduced in liver transplantation to improve …
machine perfusion (D-HOPE) was introduced in liver transplantation to improve …
[HTML][HTML] Aktualisierte S2k-Leitlinie nicht-alkoholische Fettlebererkrankung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs-und …
E Roeb, A Canbay, H Bantel, J Bojunga… - Zeitschrift für …, 2022 - thieme-connect.com
Das Fortschreiten einer NASH ist assoziiert mit Leberzellstress, konsekutiver Entzündung
und Fibrose, mit potentieller Entwicklung einer Leberzirrhose, portaler Hypertension und der …
und Fibrose, mit potentieller Entwicklung einer Leberzirrhose, portaler Hypertension und der …
Transplantation of declined livers after normothermic perfusion
C Quintini, L Del Prete, A Simioni, L Del Angel, TD Uso… - Surgery, 2022 - Elsevier
Background The persistent shortage of liver allografts contributes to significant waitlist
mortality despite efforts to increase organ donation. Normothermic machine perfusion holds …
mortality despite efforts to increase organ donation. Normothermic machine perfusion holds …