HibeRNAtion: HIV-1 RNA metabolism and viral latency

R Crespo, S Rao, T Mahmoudi - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of
resting memory CD4+ T cells bearing replication-competent provirus. Pharmacological …

Visualization of retroviral Gag-genomic RNA cellular interactions leading to genome encapsidation and viral assembly: An overview

S Bernacchi - Viruses, 2022 - mdpi.com
Retroviruses must selectively recognize their unspliced RNA genome (gRNA) among
abundant cellular and spliced viral RNAs to assemble into newly formed viral particles …

The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation

H Ramos, A Monette, M Niu, A Barrera… - Nucleic Acids …, 2022 - academic.oup.com
Translation initiation of the viral genomic mRNA (vRNA) of human immunodeficiency virus-
type 1 (HIV-1) can be mediated by a cap-or an internal ribosome entry site (IRES) …

Staufen‐2 functions as a cofactor for enhanced Rev‐mediated nucleocytoplasmic trafficking of HIV‐1 genomic RNA via the CRM1 pathway

K Balakrishnan, P Munusami, K Mohareer… - The FEBS …, 2022 - Wiley Online Library
Nucleocytoplasmic shuttling of viral elements, supported by several host factors, is essential
for the replication of the human immunodeficiency virus (HIV). HIV‐1 uses a nuclear RNA …

A degradation motif in STAU1 defines a novel family of proteins involved in inflammation

Y Gonzalez Quesada, L DesGroseillers - International Journal of …, 2022 - mdpi.com
Cancer development is regulated by inflammation. Staufen1 (STAU1) is an RNA-binding
protein whose expression level is critical in cancer cells as it is related to cell proliferation or …

Extensive uORF translation from HIV-1 transcripts conditions DDX3 dependency for expression of main ORFs and elicits specific T cell immune responses in infected …

E Labaronne, D Décimo, L Bertrand, L Guiguettaz… - bioRxiv, 2022 - biorxiv.org
Human immunodeficiency virus type-1 (HIV-1) is a complex retrovirus which relies on
alternative splicing, translational and post-translational mechanisms to produce more than …

Impact sur la relation hôte-pathogène de l'interaction entre l'hélicase UPF1 et les transporteurs rétroviraux, Rex d'HTLV-1 et Rev d'HIV-1

L Prochasson - 2022 - theses.hal.science
De par son rôle central dans plusieurs voies de dégradation de l'ARN, l'hélicase UPF1 (UP-
Frameshift 1) est associée à différents processus cellulaires contrôlant la stabilité de l'ARN …

La protéine Staufen1 contrôle la localisation des ARN spécifiques sur le fuseau mitotique dans les cellules de cancer colorectal humain HCT116

S Hassine - 2022 - papyrus.bib.umontreal.ca
La protéine de liaison à l'ARN double-brin Staufen1 (STAU1) est exprimée dans les cellules
de mammifères de manière ubiquitaire. STAU1 est impliqué dans la régulation post …

[图书][B] Genome scale identification of HIV Dependency factors across multiple HIV-1 strains

VR Montoya - 2022 - search.proquest.com
In this thesis, I developed a method called HIV-CRISPR screening at genome-wide scale,
and then at a smaller, targeted scale, to uncover novel genes that may act as HIV-1 …