Objective: To determine the associations of demographic, clinical, laboratory, organ
dysfunction, and illness severity variable values with: 1) sepsis, severe sepsis, or septic …

During sepsis, an initial prothrombotic shift takes place, in which coagulatory acute-phase
proteins are increased, while anticoagulatory factors and platelet count decrease. Further …

CONTEXT Prior criteria to define pediatric multiple organ dysfunction syndrome (MODS) did
not include gastrointestinal dysfunction. OBJECTIVES Our objective was to evaluate current …

Background Existing scoring systems have limitations in predicting the in-hospital mortality
of adult sepsis patients. We aimed to develop and validate a novel risk score for predicting …

CONTEXT Studies of organ dysfunction in children are limited by a lack of consensus
around organ dysfunction criteria. OBJECTIVES To derive evidence-informed, consensus …