[HTML][HTML] Diagnosis and treatment of therapy-related acute myeloid leukemia

SA Strickland, N Vey - Critical reviews in oncology/hematology, 2022 - Elsevier
Therapy-related acute myeloid leukemia (t-AML), defined as AML arising from prior
cytotoxic, radiation, or immunosuppressive therapy for an unrelated disease, accounts for …

Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia

AH Matthews, AE Perl, SM Luger, AW Loren… - Blood …, 2022 - ashpublications.org
CPX-351 and venetoclax and azacitidine (ven/aza) are both indicated as initial therapy for
acute myeloid leukemia (AML) in older adults. In the absence of prospective randomized …

[HTML][HTML] Measurable residual disease in high-risk acute myeloid leukemia

T Cluzeau, RM Lemoli, J McCloskey, T Cooper - Cancers, 2022 - mdpi.com
Simple Summary Assessment of measurable residual disease (MRD) identifies small
numbers of acute myeloid leukemia (AML) cells that may remain after initiating treatment …

In-depth time-dependent analysis of the benefit of allo-HSCT for elderly patients with CR1 AML: a FILO study

R Devillier, E Forcade, A Garnier… - Blood …, 2022 - ashpublications.org
The benefit of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for patients
with acute myeloid leukemia (AML) aged> 60 years remains a matter of debate, notably …

[HTML][HTML] Refining AML treatment: the role of genetics in response and resistance evaluation to new agents

A Halik, CM Arends, L Bullinger, F Damm, M Frick - Cancers, 2022 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is an aggressive cancer of the
hematopoietic system. At present, we know that AML is heterogeneous and varies from one …

[HTML][HTML] CPX-351: An Old Scheme with a New Formulation in the Treatment of High-Risk AML

M Molica, S Perrone, C Mazzone, L Cesini… - Cancers, 2022 - mdpi.com
Simple Summary Secondary AML (s-AML) including therapy-related acute myeloid leukemia
(t-AML) and acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) …

[HTML][HTML] Clinical and Cytogenetic Characterization of Early and Late Relapses in Patients Allografted for Myeloid Neoplasms with a Myelodysplastic Component

V Platte, A Bergmann, B Hildebrandt, D Wieczorek… - Cancers, 2022 - mdpi.com
Simple Summary Relapse as the most common reason for treatment failure after allogeneic
hematopoietic stem-cell transplantation (allo-SCT) in myeloid neoplasms usually occurs …

[HTML][HTML] Diagnostic Workup of Acute Myeloid Leukemia: What Is Really Necessary? An Italian Survey

MT Voso, F Ferrara, S Galimberti, A Rambaldi… - Frontiers in …, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is a heterogeneous disease with a wide variety of clinical
presentations, morphological features, and immunophenotypes. The diagnostic approaches …

Cost-effectiveness of liposomal cytarabine/daunorubicin in patients with newly diagnosed acute myeloid leukemia

JP Bewersdorf, KK Patel, G Goshua… - Blood, The Journal …, 2022 - ashpublications.org
The liposomal formulation of cytarabine/daunorubicin (CPX-351) has been shown to
improve overall survival (OS) in older (60-75 years of age) patients with newly diagnosed …

Comparison of hospital length of stay and supportive care utilization between patients treated with CPX-351 and 7+ 3 for therapy-related acute myeloid leukemia or …

K Price, Z Cao, C Lipkin, D Profant… - … and Outcomes Research, 2022 - Taylor & Francis
Purpose CPX-351 is dual-drug liposomal encapsulation of daunorubicin and cytarabine at a
fixed synergistic 1: 5 molar ratio. This study determined current real-world use of CPX-351 …