Neurological disorders are a group of disorders with motor, sensory or cognitive damage,
caused by dysfunction of the central or peripheral nervous system. Cyclin-dependent …

Previous studies on the mechanisms of peripheral nerve injury (PNI) have mainly focused
on the pathophysiological changes within a single injury site. However, recent studies have …

Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent monogenic
human disease, but to date, only one therapy (tolvaptan) is approved to treat kidney cysts in …

Mechanistic studies principally focusing on primary afferent nociceptive neurons uncovered
the upregulation of collapsin response mediator protein 2 (CRMP2)—a dual trafficking …

Background and Purpose An increasing number of autoimmune encephalitis (AE)-
associated autoantibodies have been successfully characterized. However, many cases of …

Dysregulation of voltage-gated sodium NaV1. 7 channels in sensory neurons contributes to
chronic pain conditions, including trigeminal neuropathic pain. We previously reported that …

Chronic neuropathic pain results from a malfunction of the sensory nervous system initially
wired to perceive pain as a protective mechanism against tissue injury and damage. The first …