[PDF][PDF] Contexts and contradictions: a roadmap for computational drug repurposing with knowledge inference
DN Sosa, RB Altman - Briefings in bioinformatics, 2022 - academic.oup.com
The cost of drug development continues to rise and may be prohibitive in cases of unmet
clinical need, particularly for rare diseases. Artificial intelligence-based methods are …
clinical need, particularly for rare diseases. Artificial intelligence-based methods are …
[HTML][HTML] Ontology-based identification and prioritization of candidate drugs for epilepsy from literature
Background Drug repurposing can improve the return of investment as it finds new uses for
existing drugs. Literature-based analyses exploit factual knowledge on drugs and diseases …
existing drugs. Literature-based analyses exploit factual knowledge on drugs and diseases …
[HTML][HTML] Computationally repurposing drugs for breast cancer subtypes using a network-based approach
Abstract 'De novo'drug discovery is costly, slow, and with high risk. Repurposing known
drugs for treatment of other diseases offers a fast, low-cost/risk and highly-efficient method …
drugs for treatment of other diseases offers a fast, low-cost/risk and highly-efficient method …
Analysis of Drug Repositioning and Prediction Techniques: A Concise Review
S He, X Liu, X Ye, S Tetsuya - Current Topics in Medicinal …, 2022 - ingentaconnect.com
High costs and risks are common issues in traditional drug research and development.
Usually, it takes a long time to research and develop a drug, the effects of which are limited …
Usually, it takes a long time to research and develop a drug, the effects of which are limited …
[HTML][HTML] Expanding a database-derived biomedical knowledge graph via multi-relation extraction from biomedical abstracts
DN Nicholson, DS Himmelstein, CS Greene - BioData Mining, 2022 - Springer
Background Knowledge graphs support biomedical research efforts by providing contextual
information for biomedical entities, constructing networks, and supporting the interpretation …
information for biomedical entities, constructing networks, and supporting the interpretation …
Identifying Network Biomarkers for Each Breast Cancer Subtypes Along with Their Effective Single and Paired Repurposed Drugs Using Network-Based Machine …
F Firoozbakht - 2022 - search.proquest.com
Breast cancer is a complex disease that can be classified into at least 10 different molecular
subtypes. Appropriate diagnosis of specific subtypes is critical for ensuring the best possible …
subtypes. Appropriate diagnosis of specific subtypes is critical for ensuring the best possible …