A novel anti‐c‐Kit antibody–drug conjugate to treat wild‐type and activating‐mutant c‐Kit‐positive tumors

JO Kim, KH Kim, EJ Baek, B Park, MK So… - Molecular …, 2022 - Wiley Online Library
c‐Kit overexpression and activating mutations, which are reported in various cancers,
including gastrointestinal stromal tumor (GIST), small‐cell lung cancer (SCLC), acute …

[HTML][HTML] Small cell lung cancer: an overview of the targets

BN Valadares, MA Stephano - Brazilian Journal of Pharmaceutical …, 2022 - SciELO Brasil
Lung cancer is the leading cause of cancer deaths worldwide. Small cell lung cancer
(SCLC) accounts for approximately 15% of all lung cancer cases. Despite a frequently good …

[HTML][HTML] Antibody-drug conjugate targeting c-Kit for the treatment of small cell lung cancer

KH Kim, JO Kim, JY Park, MD Seo, SG Park - International Journal of …, 2022 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths. Small cell lung cancer (SCLC)
accounts for 15–25% of all lung cancers. It exhibits a rapid doubling time and a high degree …