Alcoholic liver disease: a new insight into the pathogenesis of liver disease
Excessive alcohol consumption contributes to a broad clinical spectrum of liver diseases,
from simple steatosis to end-stage hepatocellular carcinoma. The liver is the primary organ …
from simple steatosis to end-stage hepatocellular carcinoma. The liver is the primary organ …
[HTML][HTML] Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH)
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
[HTML][HTML] Advancements in the alcohol-associated liver disease model
L Zhu, HD Li, JJ Xu, JJ Li, M Cheng, XM Meng… - Biomolecules, 2022 - mdpi.com
Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad
spectrum of liver damage. The presentation of ALD can include simple steatosis …
spectrum of liver damage. The presentation of ALD can include simple steatosis …
Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice
DJ Samuvel, L Li, Y Krishnasamy, M Gooz… - Autophagy, 2022 - Taylor & Francis
Ethanol increases hepatic mitophagy driven by unknown mechanisms. Type 1 mitophagy
sequesters polarized mitochondria for nutrient recovery and cytoplasmic remodeling. In …
sequesters polarized mitochondria for nutrient recovery and cytoplasmic remodeling. In …
[HTML][HTML] Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment
Z Ma, X Xue, J Bai, Y Cai, X Jin, K Jia, M Ding… - Biomedicine & …, 2022 - Elsevier
Abstract Si-Wu-Tang (SWT), a traditional Chinese medicine formula firstly recorded from the
Tang dynasty, has been reported to alleviate gynecological and liver diseases. We …
Tang dynasty, has been reported to alleviate gynecological and liver diseases. We …
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles
Y Li, R Liu, M Ding, Q Zheng, J Wu, X Xue… - Acta Pharmacologica …, 2022 - nature.com
Liver fibrosis is the common consequence of almost all liver diseases and has become an
urgent clinical problem without efficient therapies. Recent evidence has shown that …
urgent clinical problem without efficient therapies. Recent evidence has shown that …
Deep transfer learning for automated liver cancer gene recognition using spectrogram images of digitized DNA sequences
DNA biomarkers are considered to be an important diagnostic factor for early detection of
cancer. With the development of technology, many machine learning methods have been …
cancer. With the development of technology, many machine learning methods have been …
[HTML][HTML] Aldehyde accumulation in aged alcoholic beer: addressing acetaldehyde impacts on upper aerodigestive tract cancer risks
MTG Moreira, PR Pereira, A Aquino… - International journal of …, 2022 - mdpi.com
Aldehydes, particularly acetaldehyde, are carcinogenic molecules and their concentrations
in foodstuffs should be controlled to avoid upper aerodigestive tract (UADT) and liver …
in foodstuffs should be controlled to avoid upper aerodigestive tract (UADT) and liver …
ALDH2 hampers immune escape in liver hepatocellular carcinoma through ROS/Nrf2-mediated autophagy
J Hu, L Yang, X Peng, M Mao, X Liu, J Song, H Li - Inflammation, 2022 - Springer
Abstract Aldehyde dehydrogenase 2 (ALDH2) has been implicated in the progression of
liver hepatocellular carcinoma (LIHC). The most important feature of LIHC is the immune …
liver hepatocellular carcinoma (LIHC). The most important feature of LIHC is the immune …
[HTML][HTML] HBx mediated increase of DDX17 contributes to HBV-related hepatocellular carcinoma tumorigenesis
ML Dong, X Wen, X He, JH Ren, HB Yu… - Frontiers in …, 2022 - frontiersin.org
HBV is strongly associated with HCC development and DEAD-box RNA helicase 17
(DDX17) is a very important member of the DEAD box family that plays key roles in HCC …
(DDX17) is a very important member of the DEAD box family that plays key roles in HCC …