The endoplasmic reticulum (ER) is a large continuous membranous organelle that plays a
central role as the hub of protein and lipid synthesis while the mitochondria is the principal …

Abstract Ambient particulate matter 2.5 (PM 2.5) exposure has been linked to pulmonary
fibrosis. However, the key signaling pathways remained unclear. In the present study, we …

Surfactin, produced by Bacillus amyloliquefaciens fmb50, was used to treat insulin‐resistant
(IR) hepatocyte. It was found that surfactin increased glucose consumption in insulin …

Inositol-requiring enzyme 1 (IRE1) is an evolutionarily conserved sensor of endoplasmic
reticulum (ER) stress and mediates a key branch of the unfolded protein response in …

Most cellular protein synthesis, including synthesis of membrane-targeted and secreted
proteins, which are critical for cellular and organ crosstalk, takes place at the endoplasmic …

Receptor for activated C kinase 1 (RACK1) is a versatile protein involved in multiple
biological processes. In a previous study by Zhao et al., hepatic RACK1 deletion in mice led …

Abstract Transforming Growth Factor β1 (TGFβ1) is a critical regulator of tumor progression
in response to HRas. Recently, TGFβ1 has been shown to trigger ER stress in many disease …

Long noncoding RNAs (lncRNAs) have been reported to have multiple functions and can be
used as markers of various diseases, including diabetes. This study was conducted to …

The ribosome is a macromolecular system that has a significant role in synthesizing protein
within all living cells. Ribosome in eucaryotic cell consists of two subunits; including small …

L'obésité est un problème de santé publique majeur au niveau mondial. En France, plus de
50% de la population est en surpoids ou obèse. L'obésité s' accompagne de pathologies …