[HTML][HTML] European Association of Urology guidelines on renal cell carcinoma: the 2022 update

B Ljungberg, L Albiges, Y Abu-Ghanem, J Bedke… - European urology, 2022 - Elsevier
Abstract Context The European Association of Urology (EAU) Renal Cell Carcinoma (RCC)
Guideline Panel has prepared evidence-based guidelines and recommendations for the …

[HTML][HTML] Efficacy and safety of first-line systemic therapy for metastatic renal cell carcinoma: a systematic review and network meta-analysis

NA Bosma, MT Warkentin, CL Gan, S Karim… - European urology open …, 2022 - Elsevier
Context Considerable advances have been made in the first-line treatment of metastatic
renal cell carcinoma (mRCC), with immunotherapy-based combinations including …

Management of metastatic clear cell renal cell carcinoma: ASCO guideline

WK Rathmell, RB Rumble… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To provide recommendations for the management of patients with metastatic
clear cell renal cell carcinoma (ccRCC). METHODS An Expert Panel conducted a systematic …

Renal cell carcinoma therapy: current and new drug candidates

O Pontes, S Oliveira-Pinto, F Baltazar, M Costa - Drug Discovery Today, 2022 - Elsevier
Renal cell carcinoma (RCC) is the most common and lethal tumor of the urological system.
Curative treatment of localized RCC includes nephrectomy, radio-ablation, and active …

Phase II trial of stereotactic ablative radiation for oligoprogressive metastatic kidney cancer

R Hannan, M Christensen, H Hammers… - European urology …, 2022 - Elsevier
Background Patients with metastatic renal cell carcinoma (mRCC) treated with systemic
therapy sometimes progress at limited sites. The best treatment approach for patients with …

Stereotactic Ablative Radiation for Systemic Therapy–naïve Oligometastatic Kidney Cancer

R Hannan, M Christensen, A Christie, A Garant… - European urology …, 2022 - Elsevier
Background Evidence-based guidelines for the management of systemic therapy–naïve
oligometastatic renal cell carcinoma (RCC) are lacking. Objective To evaluate the potential …

Associations between pretreatment body composition features and clinical outcomes among patients with metastatic clear cell renal cell carcinoma treated with …

Y Ged, A Sanchez, S Patil, A Knezevic, E Stein… - Clinical Cancer …, 2022 - AACR
Purpose: High body mass index (BMI) may lead to improved immune-checkpoint blockade
(ICB) outcomes in metastatic clear cell renal cell carcinoma (mccRCC). However, BMI is a …

[HTML][HTML] The emerging role of radiation therapy in renal cell carcinoma

M Christensen, R Hannan - Cancers, 2022 - mdpi.com
Simple Summary Stereotactic ablative radiation therapy (SAbR) is a safe and effective local
therapy for renal cell cancer (RCC) with emerging and evolving indications. In this review we …

[HTML][HTML] Development of a phagocytosis-dependent gene signature to predict prognosis and response to checkpoint inhibition in clear-cell renal cell carcinoma

K Li, Y Li, Y Lyu, L Tan, X Zheng, H Jiang… - Frontiers in …, 2022 - frontiersin.org
Aim The action of immune checkpoint inhibition (ICI) largely depends on antibody-
dependent cellular phagocytosis (ADCP). We thus aim to develop ADCP-based ccRCC risk …

[HTML][HTML] The association between a decrease in on-treatment neutrophil-to-eosinophil ratio (NER) at week 6 after ipilimumab plus nivolumab initiation and improved …

YW Chen, MD Tucker, LC Brown, HA Yasin, KK Ancell… - Cancers, 2022 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) have significantly changed the
treatment paradigm in metastatic renal cell carcinoma (mRCC) and brought an …