Bladder cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

T Powles, J Bellmunt, E Comperat… - Annals of …, 2022 - annalsofoncology.org
Urothelial carcinoma (UC), also described as bladder cancer, is the 10th most common
cancer type worldwide, with an estimated 549 000 new cases and 200 000 deaths in 2018 …

Neoadjuvant chemotherapy before nephroureterectomy in high-risk upper tract urothelial cancer: a systematic review and meta-analysis

D Oswald, M Pallauf, S Deininger, P Törzsök… - Cancers, 2022 - mdpi.com
Simple Summary In muscle-invasive bladder cancer, platinum-based neoadjuvant
chemotherapy is a well-established concept, since it contributes to pathological …

A systematic review and meta-analysis of prognostic nomograms after UTUC surgery

M Pallauf, F Koenig, D D'Andrea, E Laukhtina… - Frontiers in …, 2022 - frontiersin.org
Background Current guidelines recommend assessing the prognosis in high-risk upper tract
urothelial carcinoma patients (UTUC) after surgery. However, no specific method is …

[HTML][HTML] Single-cell atlases link macrophages and CD8+ T-cell subpopulations to disease progression and immunotherapy response in urothelial carcinoma

Y Liang, Y Tan, B Guan, B Guo, M Xia, J Li, Y Shi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Abstract Rationale: Immune checkpoint inhibitors (ICIs) have revolutionized the
management of locally advanced or metastatic urothelial carcinoma. Strikingly, compared to …

Perioperative circulating tumor DNA enables the identification of patients with poor prognosis in upper tract urothelial carcinoma

K Nakano, Y Koh, G Yamamichi, S Yumiba… - Cancer …, 2022 - Wiley Online Library
Perioperative systemic chemotherapy improves the prognosis of upper tract urothelial
carcinoma (UTUC). The first objective of this study was to verify whether perioperative …

Urinary tract tumor organoids reveal eminent differences in drug sensitivities when compared to 2-dimensional culture systems

Y Wei, B Amend, T Todenhoefer, N Lipke… - International Journal of …, 2022 - mdpi.com
Generation of organoids from urinary tract tumor samples was pioneered a few years ago.
We generated organoids from two upper tract urothelial carcinomas and from one bladder …

Prognostic significance of organ-specific metastases in patients with metastatic upper tract urothelial carcinoma

A Tufano, N Cordua, V Nardone, R Ranavolo… - Journal of Clinical …, 2022 - mdpi.com
Background: Existing data on metastatic upper tract urothelial carcinoma (mUTUC) are
limited. In this study, we investigated the prognostic value of site-specific metastases in …

Patient‐derived upper tract urothelial carcinoma organoids as a platform for drug screening

Z Li, H Xu, Y Gong, W Chen, Y Zhan, L Yu… - Advanced …, 2022 - Wiley Online Library
Upper tract urothelial carcinomas (UTUCs) are rare entities that are usually diagnosed at
advanced stages. Research on UTUC pathobiology and clinical management has been …

Robotic radical nephroureterectomy with bladder cuff excision for upper tract urothelial carcinoma: A trend analysis of utilization and a comparative study

H Bae, JH Chung, W Song, M Kang, HG Jeon… - Cancers, 2022 - mdpi.com
Simple Summary Robotic radical nephroureterectomy (RNU) for patients with upper tract
urothelial carcinoma has only recently started to increase in Korea. The use of robotic RNU …

Tumor size predicts muscle-invasive and non–organ-confined disease in upper tract urothelial carcinoma at radical nephroureterectomy

CC Ruvolo, L Nocera, LF Stolzenbach, M Wenzel… - European Urology …, 2022 - Elsevier
Background Pathological stage and grade of renal pelvis urothelial carcinoma (RPUC) are
difficult to estimate before radical nephroureterectomy (RNU). Objective To examine tumor …