Understanding the developmental origins of health and disease is integral to overcome the
global tide of obesity and its metabolic consequences, including atherosclerotic …

Background Compared to the exhaustive study of transgenerational programming of obesity
and diabetes through exposures in the prenatal period, postnatal programming mechanisms …

Lactation is a crucial postnatal programming window which can interfere with child
development and predispose to metabolic disorders later in life, as insulin resistance and …

Lactation is a critical period of development and alterations in milk composition due to
maternal diet or status may affect infant growth. We aimed to evaluate in rats whether …

While a dramatic increase in obesity and related comorbidities is being witnessed, the
underlying mechanisms of their spread remain unresolved. Epigenetic and other non …

Background Maternal high-fat diet (HFD) during pregnancy and lactation exerts long-term
effects on the health of offspring. However, the critical developmental window for metabolic …

This study aimed to investigate the effect of maternal high-fat (HF) diet and exercise during
gestation and lactation on hypothalamic neural projection development in the offspring …

Introduction and Objectives: Lactation is considered a critical phase for the development of
metabolic disease and for the programming of neuronal changes in adult life. Although the …

We evaluated whether protein restriction in fetal life alters food intake and glucose
homeostasis in adulthood by interfering with insulin signal transduction through …

Obesity and related diseases are deeply rooted in both hereditary and environmental
aspects that may originate in childhood (Morris, 2009). A range of clinical and experimental …