Bone metastasis remains a challenge in cancer treatment. Here we show enzymatic
responsive rigid-rod aromatics acting as the substrates of “undruggable” phosphatases to …

While early genetic and low-resolution structural observations suggested that extracellular
conductive filaments on metal-reducing organisms such as Geobacter were composed of …

Synthetic peptide and peptido-mimetic filaments and tubes represent a diverse class of
nanomaterials with a broad range of potential applications, such as drug delivery, vaccine …

While biofilms formed by bacteria have received great attention due to their importance in
pathogenesis, much less research has been focused on the biofilms formed by archaea. It …

The recent revolution in cryo-electron microscopy (cryo-EM) has made it possible to
determine macromolecular structures directly from cell extracts. However, identifying the …

Phenol-soluble modulins (PSMs) are peptide-based virulence factors that play significant
roles in the pathogenesis of staphylococcal strains in community-associated and hospital …

The interplay of crystalline packing, which governs atomic length-scale order, and
hierarchical assembly, which governs longer length scales, is essential to fabricate complex …