Enhanced permeability and retention effect: A key facilitator for solid tumor targeting by nanoparticles

VR Shinde, N Revi, S Murugappan, SP Singh… - Photodiagnosis and …, 2022 - Elsevier
Exploring the enhanced permeability and retention (EPR) effect through therapeutic
nanoparticles has been a subject of considerable interest in tumor biology. This passive …

Bioinspired artificial platelets: past, present and future

NF Luc, N Rohner, A Girish, U Didar Singh Sekhon… - Platelets, 2022 - Taylor & Francis
Platelets are anucleate blood cells produced from megakaryocytes predominantly in the
bone marrow and released into blood circulation at a healthy count of 150,000–400, 00 per …

Drug delivery through nanoparticles in solid tumors: a mechanistic understanding

FM Kashkooli, M Rezaeian, M Soltani - Nanomedicine, 2022 - Taylor & Francis
Aim: In this study, the main goal was to apply a multi-scale computational model in
evaluating nano-sized drug-delivery systems, following extracellular drug release, into solid …

Multicolor super-resolution microscopy of protein corona on single nanoparticles

Y Wang, PED Soto Rodriguez, L Woythe… - … Applied Materials & …, 2022 - ACS Publications
Nanoparticles represent a promising class of material for nanomedicine and molecular
biosensing. The formation of a protein corona due to nonspecific particle–protein …

Nanotherapeutics in tumour microenvironment for cancer therapy

D Rana, S Salave, S Longare… - Nanoscience & …, 2022 - ingentaconnect.com
Background: Cancer continues to be the most annihilating illness and despite vast research
in understanding cancer biology as well as rational drug designing progressing profoundly …

Unsteady 3D micropolar nanofluid flow through a squeezing channel: application to cardiovascular disorders

D Sastry, NN Kumar, PK Kameswaran, S Shaw - Indian Journal of Physics, 2022 - Springer
Micropolar fluids had many industrial applications such as polymer solutions, lubricant
fluids, and biological structures. However, the present study deals with the drug delivery in …

Vertex protein PduN tunes encapsulated pathway performance by dictating bacterial metabolosome morphology

CE Mills, C Waltmann, AG Archer, NW Kennedy… - Nature …, 2022 - nature.com
Engineering subcellular organization in microbes shows great promise in addressing
bottlenecks in metabolic engineering efforts; however, rules guiding selection of an …

Mechanical characterization of soft microparticles prepared by droplet microfluidics

E Kim, H Lee - Journal of Polymer Science, 2022 - Wiley Online Library
Droplet microfluidics is one of the most promising approaches that allows preparation of
microparticles with tailored structure and composition. Various functional microparticles …

Shape-specific microfabricated particles for biomedical applications: a review

TL Moore, AB Cook, E Bellotti, R Palomba… - Drug delivery and …, 2022 - Springer
The storied history of controlled the release systems has evolved over time; from degradable
drug-loaded sutures to monolithic zero-ordered release devices and nano-sized drug …

Tuning three-dimensional nano-assembly in the mesoscale via bis (imino) pyridine molecular functionalization

R Brisbin, M Bartolo, M Leville, AK Rajan, B Jahan… - Scientific Reports, 2022 - nature.com
We investigate the effect of bis (imino) pyridine (BIP) ligands in guiding self-assembly of
semiconducting CdSe/ZnS quantum dots (QDs) into three-dimensional multi-layered shells …