Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …

Accelerated biological aging, which involves the gradual decline of organ or tissue functions
and the distortion of physiological processes, underlies several human diseases. Away from …

Background Millions of people suffer from Alzheimer's disease (AD) and Parkinson's
disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …

Alzheimer's disease (AD) is presented as an age-related neurodegenerative disease with
multiple cognitive deficits and amyloid β (Aβ) accumulation is the most important involved …

Nobiletin (Nob), a critical active flavonoid of citrus fruits, has received attention for its
superior physical functions, which have shown to improve the progression of diseases …

Abstract Alzheimer's disease (AD), the most prevalent neurodegenerative disorder, is largely
associated with cognitive disability, amnesia, and abnormal behavior, which accounts for …

Objective This study aimed to explore the mechanism of Nobiletin attenuating Alzheimer's
disease (AD) by inhibiting neuroinflammation. Methods The expression of inflammatory …

Environmental exposure to arsenic has been profoundly associated with chronic systemic
disorders, such as neurodegeneration, in both experimental models and clinical studies …

Polymethoxyflavonoids (PMFs) are a large group of compounds belonging to the more
general class of flavonoids that possess a flavan carbon framework decorated with a …

Delirium is a common and serious neuropsychiatric syndrome characterized with acute
cognitive and attentional deficits, however, the effective therapies are lacking. Here, using …