Lung cancer stem cell markers as therapeutic targets: an update on signaling pathways and therapies
Y Zheng, L Wang, L Yin, Z Yao, R Tong, J Xue… - Frontiers in …, 2022 - frontiersin.org
Cancer stem cells, a relatively small group of self-renewing cancer cells, were first isolated
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …
How mechanisms of stem cell polarity shape the human cerebral cortex
MG Andrews, L Subramanian, J Salma… - Nature Reviews …, 2022 - nature.com
Apical–basal progenitor cell polarity establishes key features of the radial and laminar
architecture of the developing human cortex. The unique diversity of cortical stem cell …
architecture of the developing human cortex. The unique diversity of cortical stem cell …
Role of CD133/NRF2 axis in the development of colon cancer stem cell-like properties
J Park, SK Kim, SP Hallis, BH Choi, MK Kwak - Frontiers in Oncology, 2022 - frontiersin.org
Cancer stem cells (CSCs) exhibit intrinsic therapy/stress resistance, which often cause
cancer recurrence after therapy. In this study, we investigated the potential relationship …
cancer recurrence after therapy. In this study, we investigated the potential relationship …
Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium
Differences in ciliary morphology and dynamics among multiciliated cells of the respiratory
tract contribute to efficient mucociliary clearance. Nevertheless, little is known about how …
tract contribute to efficient mucociliary clearance. Nevertheless, little is known about how …
Asymmetric pericentrosomal CD133 endosomes induce the unequal autophagic activity during cytokinesis in CD133-positive human neuroblastoma cells
H Izumi, Y Li, M Yasunami, S Sato, T Mae… - Stem Cells, 2022 - academic.oup.com
CD133 is a transmembrane protein that mainly localizes to the plasma membrane in
hematopoietic/neural stem cells and cancer stem cells. Although CD133 also localizes to the …
hematopoietic/neural stem cells and cancer stem cells. Although CD133 also localizes to the …
A lateral protrusion latticework connects neuroepithelial cells and is regulated during neurogenesis
Dynamic contacts between cells within the developing neuroepithelium are poorly
understood but play important roles in cell and tissue morphology and cell signalling. Here …
understood but play important roles in cell and tissue morphology and cell signalling. Here …
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis
N Kotani, T Nakano, R Kuwahara - Journal of Biological Chemistry, 2022 - ASBMB
Coronavirus disease represents a real threat to the global population, and understanding
the biological features of the causative virus, that is, severe acute respiratory syndrome …
the biological features of the causative virus, that is, severe acute respiratory syndrome …
FASN-dependent de novo lipogenesis is required for brain development
D Gonzalez-Bohorquez… - Proceedings of the …, 2022 - National Acad Sciences
Fate and behavior of neural progenitor cells are tightly regulated during mammalian brain
development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that …
development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that …
[HTML][HTML] The prominin-like gene expressed in a subset of dopaminergic neurons regulates locomotion in Drosophila
CD133, also known as prominin-1, was first identified as a biomarker of mammalian cancer
and neural stem cells. Previous studies have shown that the prominin-like (promL) gene, an …
and neural stem cells. Previous studies have shown that the prominin-like (promL) gene, an …
A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis
K Baur, Y Abdullah, C Mandl, G Hölzl‐Wenig, Y Shi… - EMBO …, 2022 - embopress.org
According to the current consensus, murine neural stem cells (NSCs) apically contacting the
lateral ventricle generate differentiated progenitors by rare asymmetric divisions or by …
lateral ventricle generate differentiated progenitors by rare asymmetric divisions or by …