[HTML][HTML] The heart in congenital diaphragmatic hernia: Knowns, unknowns, and future priorities

N Patel, AC Massolo, US Kraemer… - Frontiers in …, 2022 - frontiersin.org
There is growing recognition that the heart is a key contributor to the pathophysiology of
congenital diaphragmatic hernia, in conjunction with developmental abnormalities of the …

Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia

PT Levy, J Levin, KT Leeman, MP Mullen… - Seminars in Fetal and …, 2022 - Elsevier
Chronic pulmonary hypertension of infancy (cPHi) is a heterogeneous disease process that
contributes to morbidity and mortality in preterm infants. cPHi is most commonly associated …

Characterisation of paediatric pulmonary hypertensive vascular disease from the PPHNet Registry

SH Abman, MP Mullen, LA Sleeper… - European …, 2022 - Eur Respiratory Soc
Background There are limited data about the range of diseases, natural history, age-
appropriate end-points and optimal care for children with pulmonary hypertension (PH) …

Risk factors of early pulmonary hypertension and its clinical outcomes in preterm infants: a systematic review and meta-analysis

YJ Kim, SH Shin, HW Park, EK Kim, HS Kim - Scientific reports, 2022 - nature.com
The aim of this meta-analysis was to determine the incidence and risk factors of early
pulmonary hypertension (PHT) in preterm infants and evaluate the association of early PHT …

ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery

DP McGlothlin, J Granton, W Klepetko… - The Journal of Heart and …, 2022 - Elsevier
Pulmonary hypertension (PH) is a risk factor for morbidity and mortality in patients
undergoing surgery and anesthesia. This document represents the first international …

Simvastatin Inhibits NLRP3 Inflammasome Activation and Ameliorates Lung Injury in Hyperoxia‐Induced Bronchopulmonary Dysplasia via the KLF2‐Mediated …

X Wang, R Huo, Z Liang, C Xu, T Chen… - Oxidative Medicine …, 2022 - Wiley Online Library
Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly found in premature
infants. Excessive inflammation and oxidative stress contribute to BPD occurrence and …

Bronchopulmonary dysplasia from chest radiographs to magnetic resonance imaging and computed tomography: adding value

NS Higano, AJ Bates, CC Gunatilaka, EB Hysinger… - Pediatric …, 2022 - Springer
Bronchopulmonary dysplasia (BPD) is a common long-term complication of preterm birth.
The chest radiograph appearance and survivability have evolved since the first description …

Risk factors for acute kidney injury after pediatric cardiac surgery: a meta-analysis

J Van den Eynde, B Delpire, X Jacquemyn, I Pardi… - Pediatric …, 2022 - Springer
Background Cardiac surgery-associated acute kidney injury (AKI) is associated with
increased morbidity and mortality in both adults and children. Objectives This study aimed to …

Advanced formulations and nanotechnology-based approaches for pulmonary delivery of sildenafil: A scoping review

REL Lazo, M Mengarda, SL Almeida… - Journal of Controlled …, 2022 - Elsevier
Oral sildenafil (SDF) is used to treat pulmonary arterial hypertension (PAH), and its
bioavailability is approximately 40%. Several formulations of nano and microparticles (for …

Area deprivation and respiratory morbidities in children with bronchopulmonary dysplasia

E Banwell, JM Collaco, GR Oates, JL Rice… - Pediatric …, 2022 - Wiley Online Library
Introduction Infants and children diagnosed with bronchopulmonary dysplasia (BPD) have a
higher likelihood of recurrent hospitalizations and asthma‐like symptoms. Socio …