Periodontitis and implant complications in diabetes

L Nibali, N Gkranias, G Mainas… - Periodontology 2000, 2022 - Wiley Online Library
Epidemiologic evidence indicates that periodontitis is more frequent in patients with
uncontrolled diabetes mellitus than in healthy controls, suggesting that it could be …

Pediatric obesity—Long‐term consequences and effect of weight loss

C Marcus, P Danielsson… - Journal of internal …, 2022 - Wiley Online Library
Childhood obesity is, according to the WHO, one of the most serious challenges of the 21st
century. More than 100 million children have obesity today. Already during childhood …

Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases

A Bleve, F Motta, B Durante, C Pandolfo… - Clinical reviews in …, 2022 - Springer
The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

Sex bias in lymphocytes: Implications for autoimmune diseases

KC Dodd, M Menon - Frontiers in Immunology, 2022 - frontiersin.org
Autoimmune diseases are characterized by a significant sex dimorphism, with women
showing increased susceptibility to disease. This is, at least in part, due to sex-dependent …

Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach

TG Richardson, DJM Crouch, GM Power… - Nature …, 2022 - nature.com
The rising prevalence of childhood obesity has been postulated as an explanation for the
increasing rate of individuals diagnosed with type 1 diabetes (T1D). In this study, we use …

[HTML][HTML] Obesity is associated with increased risk of Crohn's disease, but not ulcerative colitis: a pooled analysis of five prospective cohort studies

SSM Chan, Y Chen, K Casey, O Olen… - Clinical …, 2022 - Elsevier
Background and Aims It is unclear whether obesity is associated with the development of
inflammatory bowel disease despite compelling data from basic science studies. We …

Multiple sclerosis and obesity: The role of adipokines

J Correale, M Marrodan - Frontiers in immunology, 2022 - frontiersin.org
Multiple Sclerosis (MS), a chronic inflammatory disease of the central nervous system that
leads to demyelination and neurodegeneration has been associated with various …

[HTML][HTML] Emerging roles of adipose tissue in the pathogenesis of psoriasis and atopic dermatitis in obesity

Z Guo, Y Yang, Y Liao, Y Shi, L Zhang - JID Innovations, 2022 - Elsevier
Obesity is a growing epidemic worldwide, and it is also considered a major environmental
factor contributing to the pathogenesis of inflammatory skin diseases, including psoriasis …

Mendelian randomization as a tool to gain insights into the mosaic causes of autoimmune diseases

C Chen, P Wang, RD Zhang, Y Fang, LQ Jiang… - Autoimmunity …, 2022 - Elsevier
Autoimmune diseases (ADs) are a broad range of disorders which are characterized by long-
term inflammation and tissue damage arising from an immune response against one's own …

Biological activities underlying the therapeutic effect of quercetin on inflammatory bowel disease

YL Lyu, HF Zhou, J Yang, FX Wang… - Mediators of …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic autoimmune disorder stemming from
unrestrained immune activation and subsequent destruction of colon tissue. Genetic …