[HTML][HTML] Atherosclerosis: recent developments

JLM Björkegren, AJ Lusis - Cell, 2022 - cell.com
Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

Post-stroke cognitive impairment and dementia

NS Rost, A Brodtmann, MP Pase, SJ van Veluw… - Circulation …, 2022 - Am Heart Assoc
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

[HTML][HTML] Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis

N Sattar, DK McGuire, I Pavo, GJ Weerakkody… - Nature medicine, 2022 - nature.com
Tirzepatide is a novel, once weekly, dual GIP/GLP-1 receptor agonist and is under
development for the treatment of type 2 diabetes (T2D) and obesity. Its association with …

[HTML][HTML] Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment

Y Zhao, X Zhang, X Chen… - … journal of molecular …, 2022 - spandidos-publications.com
Stroke is the leading cause of disabilities and cognitive deficits, accounting for 5.2% of all
mortalities worldwide. Transient or permanent occlusion of cerebral vessels leads to …

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …

Prospective evaluation of smartwatch-enabled detection of left ventricular dysfunction

ZI Attia, DM Harmon, J Dugan, L Manka… - Nature medicine, 2022 - nature.com
Although artificial intelligence (AI) algorithms have been shown to be capable of identifying
cardiac dysfunction, defined as ejection fraction (EF)≤ 40%, from 12-lead …

[HTML][HTML] Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications

D Abrams, G MacLaren, R Lorusso, S Price… - Intensive Care …, 2022 - Springer
Rates of survival with functional recovery for both in-hospital and out-of-hospital cardiac
arrest are notably low. Extracorporeal cardiopulmonary resuscitation (ECPR) is emerging as …

Global, regional, and national burden of ischaemic heart disease and its attributable risk factors, 1990–2017: results from the Global Burden of Disease Study 2017

H Dai, AA Much, E Maor, E Asher… - … Journal-Quality of …, 2022 - academic.oup.com
Aims The aim of this study was to estimate the burden and risk factors for ischaemic heart
disease (IHD) in 195 countries and territories from 1990 to 2017. Methods and results Data …

[HTML][HTML] Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function

AG Spiteri, CL Wishart, R Pamphlett, G Locatelli… - Acta …, 2022 - Springer
In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …

[HTML][HTML] Propolis: Its role and efficacy in human health and diseases

N Zullkiflee, H Taha, A Usman - Molecules, 2022 - mdpi.com
With technological advancements in the medicinal and pharmaceutical industries, numerous
research studies have focused on the propolis produced by stingless bees (Meliponini tribe) …