Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

During severe inflammatory and infectious diseases, various mediators modulate the
equilibrium of vascular tone, inflammation, coagulation and thrombosis. This Review …

Patients with COVID-19 present a wide spectrum of disease severity, from asymptomatic
cases in the majority to serious disease leading to critical care and even death. Clinically …

Unrestrained activation of the complement system till the terminal products, C5a and C5b-9,
plays a pathogenetic role in acute and chronic inflammatory diseases. In endothelial cells …

Thrombotic microangiopathy (TMA) is characterized by thrombocytopenia, microangiopathic
haemolytic anaemia and end organ damage. TMAs have varying underlying …

Background Severe coronavirus disease 2019 (COVID-19) is characterized by impaired
type I interferon activity and a state of hyperinflammation leading to acute respiratory distress …

The coronavirus disease-2019 (COVID-19) caused by the SARS-CoV-2 virus may vary from
asymptomatic to severe infection with multi-organ failure and death. Increased levels of …

Abstract Coronavirus disease 2019 (COVID-19) causes acute microvascular thrombosis in
both venous and arterial structures which is highly associated with increased mortality. The …

Introduction COVID-19 vaccination has been associated with rare but severe complications
characterized by thrombosis and thrombocytopenia. Methods and Results Here we present …

Serum or plasma have been the primary focus of proteomics studies for COVID-19 to identity
biomarkers and potential drug targets. The nasal mucosal environment which consists of …