Chemical modulators for targeting autism spectrum disorders: from bench to clinic

S Lim, S Lee - Molecules, 2022 - mdpi.com
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
diverse behavioral symptoms such as repetitive behaviors, social deficits, anxiety …

Autism, heparan sulfate and potential interventions

J Alexander, G Keles, J Killingsworth, R Bronson… - Experimental …, 2022 - Elsevier
Developmental disabilities are defined as disorders that result in the limitation of function
due to impaired development of the nervous system; these disabilities can be present in the …

Global metabolic profiles in a non-human primate model of maternal immune activation: implications for neurodevelopmental disorders

JC Boktor, MD Adame, DR Rose, CM Schumann… - Molecular …, 2022 - nature.com
Epidemiological evidence implicates severe maternal infections as risk factors for
neurodevelopmental disorders, such as ASD and schizophrenia. Accordingly, animal …

[HTML][HTML] A Computational Framework for Studying Gut-Brain Axis in Autism Spectrum Disorder

FK Mohammad, MV Palukuri, S Shivakumar… - Frontiers in …, 2022 - frontiersin.org
Introduction The integrity of the intestinal epithelium is crucial for human health and is
harmed in autism spectrum disorder (ASD). An aberrant gut microbial composition resulting …

[HTML][HTML] Influence of prenatal drug exposure, maternal inflammation, and parental aging on the development of autism spectrum disorder

A Sato, H Kotajima-Murakami, M Tanaka… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) affects reciprocal social interaction and produces abnormal
repetitive, restrictive behaviors and interests. The diverse causes of ASD are divided into …

Identification of methylation markers for diagnosis of autism spectrum disorder

B Zhang, X Hu, Y Li, Y Ni, L Xue - Metabolic Brain Disease, 2022 - Springer
Autism spectrum disorder (ASD) is a hereditary heterogeneous neurodevelopmental
disorder characterized by social and speech dysplasia. We collected the expression profiles …

[PDF][PDF] Mechanism of action and therapeutic targeting of microglia in autism spectrum disorder

Y Zhang, Y Xie, Z Cheng, Y Zhang, W Wang… - Adv …, 2022 - api-journal.accscience.com
Autism spectrum disorder (ASD) is a complex mental illness with a high incidence and
considerable impact. More than half of the affected individuals have self-harm behaviors …

Prenatal exposure to valproic acid induces alterations in the expression and activity of purinergic receptors in the embryonic rat brain

L Babiec, A Wilkaniec, A Adamczyk - Folia Neuropathologica, 2022 - termedia.pl
Purinergic signalling is involved in the control of several processes related to brain
development, such as neurogenesis and gliogenesis, migration and differentiation of …

Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use

DJ Londesbrough, C Brown, JS Northen… - US Patent …, 2022 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
60326674&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use

DJ Londesbrough, C Brown, JS Northen… - US Patent …, 2022 - Google Patents
This invention relates to the large-scale production of psilocybin for use in medicine. Move
particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly …