Atomic force microscopy (AFM) and its applications to bone-related research

Y Zhou, J Du - Progress in Biophysics and Molecular Biology, 2022 - Elsevier
Bone consists of organic (mostly collagen) and inorganic (mostly bioapatite mineral)
components that are organized into hierarchical structures from nano-to macro-scales that …

Revealing Layer‐Specific Ultrastructure and Nanomechanics of Fibrillar Collagen in Human Aorta via Atomic Force Microscopy Testing: Implications on Tissue …

M Asgari, N Latifi, F Giovanniello… - Advanced …, 2022 - Wiley Online Library
Soft biological tissues are natural biomaterials with structures that have evolved to perform
physiological functions, for example, conferring elasticity while preserving the mechanical …

Nanomechanical mapping of hard tissues by atomic force microscopy: An application to cortical bone

M Bontempi, F Salamanna, R Capozza, A Visani… - Materials, 2022 - mdpi.com
Force mapping of biological tissues via atomic force microscopy (AFM) probes the
mechanical properties of samples within a given topography, revealing the interplay …

Instrumented nanoindentation in musculoskeletal research

S Pei, Y Zhou, Y Li, T Azar, W Wang, DG Kim… - Progress in Biophysics …, 2022 - Elsevier
Musculoskeletal tissues, such as bone, cartilage, and muscle, are natural composite
materials that are constructed with a hierarchical structure ranging from the cell to tissue …

Highly rigid & transparent supramolecular fibrils of tyrosine

RY Adhikari, JJ Pujols - Nano Select, 2022 - Wiley Online Library
Various peptides and amino acids can self‐assemble into fibrils in a solution environment
both in vivo and in vitro. These fibrils can aggregate as amyloids in the organs of individuals …

Genetic Deletion of Menin in Mouse Mesenchymal Stem Cells: An Experimental and Computational Analysis

J Abi Rafeh, M Asgari, I Troka, L Canaff… - Journal of Bone and …, 2022 - academic.oup.com
Loss of function mutations in the MEN1 tumor suppressor gene cause the multiple endocrine
neoplasia type 1 syndrome. Menin, the MEN1 gene product, is expressed in many tissues …