Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
Hamster models of COVID-19 pneumonia reviewed: How human can they be?
AD Gruber, TC Firsching, J Trimpert… - Veterinary …, 2022 - journals.sagepub.com
The dramatic global consequences of the coronavirus disease 2019 (COVID-19) pandemic
soon fueled quests for a suitable model that would facilitate the development and testing of …
soon fueled quests for a suitable model that would facilitate the development and testing of …
Planning experiments: Updated guidance on experimental design and analysis and their reporting III
Scientists who plan to publish in British Journal of Pharmacology (BJP) must read this article
before undertaking a study. This editorial provides guidance for the design of experiments …
before undertaking a study. This editorial provides guidance for the design of experiments …
Is the future of peer review automated?
The rising rate of preprints and publications, combined with persistent inadequate reporting
practices and problems with study design and execution, have strained the traditional peer …
practices and problems with study design and execution, have strained the traditional peer …
Aging-related cerebral microvascular changes visualized using ultrasound localization microscopy in the living mouse
MR Lowerison, NVC Sekaran, W Zhang, Z Dong… - Scientific reports, 2022 - nature.com
Aging-related cognitive decline is an emerging health crisis; however, no established
unifying mechanism has been identified for the cognitive impairments seen in an aging …
unifying mechanism has been identified for the cognitive impairments seen in an aging …
GSDME is related to prognosis and response to chemotherapy in oral cancer
S Wang, MJ Zhang, ZZ Wu, SW Zhu… - Journal of dental …, 2022 - journals.sagepub.com
Gasdermin E (GSDME), as the major executive protein of pyroptosis, has been considered
to be linked to antitumor immunity in recent years. However, the role of GSDME in oral …
to be linked to antitumor immunity in recent years. However, the role of GSDME in oral …
sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury
CB Bergmann, CB McReynolds… - Proceedings of the …, 2022 - National Acad Sciences
Fatty acid composition in the Western diet has shifted from saturated to polyunsaturated fatty
acids (PUFAs), and specifically to linoleic acid (LA, 18: 2), which has gradually increased in …
acids (PUFAs), and specifically to linoleic acid (LA, 18: 2), which has gradually increased in …
Non-responsiveness to cardioprotection by ischaemic preconditioning in Ossabaw minipigs with genetic predisposition to, but without the phenotype of the metabolic …
P Kleinbongard, HR Lieder, A Skyschally… - Basic research in …, 2022 - Springer
The translation of successful preclinical and clinical proof-of-concept studies on
cardioprotection to the benefit of patients with reperfused acute myocardial infarction has …
cardioprotection to the benefit of patients with reperfused acute myocardial infarction has …
Microplastics Occurrence in the European Common Frog (Rana temporaria) from Cottian Alps (Northwest Italy)
Microplastics (MPs) pollution is arousing growing attention, yet knowledge about its
occurrence in amphibians is scant to date. With this study, we aimed to determine whether …
occurrence in amphibians is scant to date. With this study, we aimed to determine whether …
Gut-derived butyrate suppresses ocular surface inflammation
L Schaefer, H Hernandez, RA Coats, Z Yu… - Scientific reports, 2022 - nature.com
Dry eye is a common ocular inflammatory disorder characterized by tear film instability and
reduced tear production. There is increasing evidence that homeostasis of the ocular …
reduced tear production. There is increasing evidence that homeostasis of the ocular …