Protein–RNA interaction prediction with deep learning: structure matters

J Wei, S Chen, L Zong, X Gao, Y Li - Briefings in bioinformatics, 2022 - academic.oup.com
Protein–RNA interactions are of vital importance to a variety of cellular activities. Both
experimental and computational techniques have been developed to study the interactions …

Characterization of the 3'UTR of the BTD gene and identification of regulatory elements and microRNAs

GCV Silva, T Borsatto, IVD Schwartz… - Genetics and Molecular …, 2022 - SciELO Brasil
Reduced biotinidase activity is associated with a spectrum of deficiency ranging from total
deficiency to heterozygous levels, a finding that is not always explained by the pathogenic …

BRAF-V600E utilizes posttranscriptional mechanisms to amplify LPS-induced TNFα production in dendritic cells in a mouse model of Langerhans cell histiocytosis

D Minichino, K Lv, N Chu, W Tong… - Journal of leukocyte …, 2022 - academic.oup.com
Langerhans cell histiocytosis (LCH) is an inflammatory disease characterized by abnormal
dendritic cells (DCs) with hyperactive ERK signaling, called “LCH cells.” Since DCs rely on …

Introduction to Bioinformatics Resources for Post-transcriptional Regulation of Gene Expression

E Destefanis, E Dassi - Post-Transcriptional Gene Regulation, 2022 - Springer
Untranslated regions of mRNA (UTRs) are involved in defining the fate of the transcript
through processes such as mRNA localization, degradation, translation initiation regulation …

Caractérisation de l'interaction entre FUS et TDP-43, deux protéines de liaison à l'ARN impliquées dans les maladies neurodégénératives

C Demongin - 2022 - theses.hal.science
FUS et TDP-43 sont deux protéines de liaison à l'ARN qui partagent une structure similaire.
Elles sont aussi impliquées dans un nombre de fonctions semblables autour de la prise en …

Controlling the immune suppressors: miRNAs regulating NT5E, ENTPD1 and CD274

T Kordaß - 2022 - archiv.ub.uni-heidelberg.de
Cancer is one of the most common causes of death in the modern world and almost every
second person will experience a cancer disease during their lifetime. In general, cancer …