Vilazodone-phospholipid mixed micelles for enhancing oral bioavailability and reducing pharmacokinetic variability between fed and fasted states
HS El Said, A Lalatsa, AM Al-Mahallawi… - International Journal of …, 2022 - Elsevier
Despite the effectiveness and high tolerability of vilazodone (VLZ) as an antidepressant, its
use is still limited due to its poor solubility and food dependent absorption. This study aims to …
use is still limited due to its poor solubility and food dependent absorption. This study aims to …
Chondroitin sulfate-functionalized lipid nanoreservoirs: a novel cartilage-targeting approach for intra-articular delivery of cassic acid for osteoarthritis treatment
Novel intra-articular nanoreservoirs were implemented employing different cartilage
targeting approaches to improve cartilage bioavailability of a chondroprotective drug, cassic …
targeting approaches to improve cartilage bioavailability of a chondroprotective drug, cassic …
Preparation of 2-methoxyestradiol self-emulsified drug delivery system and the effect on combination therapy with doxorubicin against MCF-7/ADM cells
C Yu, C Li, H Pan, T Li, S He - AAPS PharmSciTech, 2022 - Springer
Due to the poor solubility and bioavailability of 2-methoxyestradiol (2-ME), 2-ME emulsified
drug delivery system (2-ME-SEDDS) was designed and characterized. After dilution with 5 …
drug delivery system (2-ME-SEDDS) was designed and characterized. After dilution with 5 …
Multi-strategic approaches for enhancing active transportation using self-emulsifying drug delivery system
S Poudwal, P Shende - Journal of Drug Targeting, 2022 - Taylor & Francis
Oral delivery is the most desired route of drug administration and it can be more beneficial
for patients suffering from chronic diseases wherein frequent parenteral administration of …
for patients suffering from chronic diseases wherein frequent parenteral administration of …
[图书][B] Hydrophobic Ion-Pairing Approach for Enhancing Oil Solubility of BCS Class II Drug Phenytoin and Increasing Drug Loading in Nanoemulsion to Prevent in …
DS Modi - 2022 - search.proquest.com
The present work focuses on modifying the lipophilicity of poorly water-soluble drug,
Phenytoin by forming lipophilic salt (ion-pair) with hydrophobic counterion via the ion-pairing …
Phenytoin by forming lipophilic salt (ion-pair) with hydrophobic counterion via the ion-pairing …
Effect of Chemical and Physical Enhancers on the Skin Permeation of Cromolyn Sodium
M Holman - 2022 - dc.etsu.edu
Cromolyn sodium (CS) has clinically shown to be an effective topical remedy for atopic
dermatitis, however its physiochemical properties prevent efficient passive drug delivery …
dermatitis, however its physiochemical properties prevent efficient passive drug delivery …
Solid self-emulsifying drug delivery system of domperidone for improved biopharmaceutical characteristics
SS Chowdhury - 2022 - dspace.bracu.ac.bd
The aim of this study was to use a solid-self emulsifying drug delivery system (S-SEDDS) to
increase the solubility and dissolution rate of Domperidone (DMP), a poorly soluble, weakly …
increase the solubility and dissolution rate of Domperidone (DMP), a poorly soluble, weakly …