The understanding of neurodegenerative diseases, traditionally considered to be well-
defined entities with distinguishable clinical phenotypes, has undergone a major shift over …

Introduction Extracellular vesicles (EVs) are known to have a significant role in the central
nervous system (CNS) and neurodegenerative disease. Methods PubMed, Scopus, ISI Web …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease affecting
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …

(1) Background: Huntington's disease (HD) is rare incurable hereditary neurodegenerative
disorder caused by CAG repeat expansion in the gene coding for the protein huntingtin …

Exosomes, nano‐sized extracellular vesicles, are produced via the endosomal pathway and
released in the extracellular space upon fusion of multivesicular bodies with the plasma …

Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disease and is the most
common adult motor neuron disease. The disease pathogenesis is complex with the …

Central nervous system (CNS) disease is a general term for a series of complex and diverse
diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis …

Extracellular vesicles can mediate communication between tissues, affecting the
physiological conditions of recipient cells. They are increasingly investigated in Amyotrophic …

Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease in urgent
need of disease biomarkers for the assessment of promising therapeutic candidates in …

Neurodegenerative disorders (NDs) are becoming one of the leading causes of disability
and death across the globe due to lack of timely preventions and treatments. Concurrently …