Asthma is a common and heterogeneous disease characterized by lower airway
inflammation and airflow limitation. Critical factors in asthma management include …

There is increasing evidence about the role of nitric oxide in type 2 (T2) immune response.
Fraction of exhaled nitric oxide (FeNO) is a product of airways inflammation and it is …

To the Editor, The presence of bronchodilator response (BDR) is one of the key hallmarks in
diagnosing asthma and is traditionally defined as a> 200 ml and> 12% improvement in …

Innate lymphoid cells (ILCs) are recently discovered innate immune cells that reside and self-
renew in mucosal tissues and serve as the first line of defense against various external …

Background Inhaled corticosteroids (ICS) are a cornerstone of asthma treatment. However,
their efficacy is characterized by wide variability in individual responses. Objective We …

Background Exercise‐induced bronchoconstriction (EIB) is a frequent and highly specific
symptom of childhood asthma. Inhaled corticosteroids (ICS) are the mainstay of controller …

Allergic asthma is an inflammatory bronchial disease associated with the IgE response,
allergic inflammation of the airways, recruitment of infiltrated inflammatory cells, increased …

Abstract The first NHLBI Clinical Trials Research Network was the Asthma Clinical Research
Network (ACRN 1), which was born in 1993 to perform multiple controlled clinical trials for …

PURPOSE: The CAPTAIN study showed that adding umeclidinium (UMEC) to fluticasone
furoate/vilanterol (FF/VI) led to improvements in lung function and symptom control in …

Pulmonary inflammation is a common pathological feature of a variety of diseases, of which
successful therapy with currently available anti-inflammatory drugs is limited by resistance …