Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
Impact of contaminants on microbiota: linking the gut–brain axis with neurotoxicity
J Balaguer-Trias, D Deepika, M Schuhmacher… - International Journal of …, 2022 - mdpi.com
Over the last years, research has focused on microbiota to establish a missing link between
neuronal health and intestine imbalance. Many studies have considered microbiota as …
neuronal health and intestine imbalance. Many studies have considered microbiota as …
In utero exposure to the Great Depression is reflected in late-life epigenetic aging signatures
LL Schmitz, V Duque - … of the National Academy of Sciences, 2022 - National Acad Sciences
Research on maternal-fetal epigenetic programming argues that adverse exposures to the
intrauterine environment can have long-term effects on adult morbidity and mortality …
intrauterine environment can have long-term effects on adult morbidity and mortality …
On the potential role of the antioxidant couple vitamin E/selenium taken by the oral route in skin and hair health
J Pincemail, S Meziane - Antioxidants, 2022 - mdpi.com
The relationship between oxidative stress and skin aging/disorders is well established.
Many topical and oral antioxidants (vitamins C and E, carotenoids, polyphenols) have been …
Many topical and oral antioxidants (vitamins C and E, carotenoids, polyphenols) have been …
[HTML][HTML] A cross-species comparative approach to assessing multi-and transgenerational effects of endocrine disrupting chemicals
A wide range of chemicals have been identified as endocrine disrupting chemicals (EDCs)
in vertebrate species. Most studies of EDCs have focused on exposure of both male and …
in vertebrate species. Most studies of EDCs have focused on exposure of both male and …
Epigenetic regulation of immune function in asthma
S Sharma, IV Yang, DA Schwartz - Journal of Allergy and Clinical …, 2022 - Elsevier
Asthma is a common complex respiratory disease characterized by chronic airway
inflammation and partially reversible airflow obstruction resulting from genetic and …
inflammation and partially reversible airflow obstruction resulting from genetic and …
Prenatal exposures to common phthalates and prevalent phthalate alternatives and infant DNA methylation at birth
Phthalates are a diverse group of chemicals used in consumer products. Because they are
so widespread, exposure to these compounds is nearly unavoidable. Recently, growing …
so widespread, exposure to these compounds is nearly unavoidable. Recently, growing …
PIWI-interacting RNA (piRNA) and epigenetic editing in environmental health sciences
BPU Perera, RK Morgan, KM Polemi… - Current Environmental …, 2022 - Springer
Abstract Purpose of Review The epigenome modulates gene expression in response to
environmental stimuli. Modifications to the epigenome are potentially reversible, making …
environmental stimuli. Modifications to the epigenome are potentially reversible, making …
A perspective on diet, epigenetics and complex diseases: where is the field headed next?
Dietary factors can regulate epigenetic processes during life, modulating the intracellular
pools of metabolites necessary for epigenetic reactions and regulating the activity of …
pools of metabolites necessary for epigenetic reactions and regulating the activity of …
Toxicoepigenetics and environmental health: Challenges and opportunities
The rapidly growing field of toxicoepigenetics seeks to understand how toxicant exposures
interact with the epigenome to influence disease risk. Toxicoepigenetics is a promising field …
interact with the epigenome to influence disease risk. Toxicoepigenetics is a promising field …